Tetanus natural history: Difference between revisions

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**Found in 50%-70% of autopsied cases
**Found in 50%-70% of autopsied cases


== Risk Stratification and Prognosis==
==Prognosis==
Death in about 10-20% of cases, higher among older people.
Death in about 10-20% of cases, higher among older people.


[[Laryngospasm]] (spasm of the vocal cords) and/or [[spasm]] of the [[muscles]] of [[respiration]] leads to interference with [[breathing]]. [[Fractures]] of the [[spine]] or [[long bones]] may result from sustained [[contractions]] and [[convulsions]]. Hyperactivity of the [[autonomic nervous system]] may lead to [[hypertension]] and/or an abnormal [[heart rhythm]]. [[Nosocomial infections]] are common because of prolonged hospitalization.
In recent years:


Secondary infections may include [[sepsis]] from indwelling [[catheters]], hospital-acquired [[pneumonias]], and [[decubitus ulcers]]. [[Pulmonary embolism]] is particularly a problem in drug users and elderly patients. [[Aspiration pneumonia]] is a common late complication of tetanus, found in 50%–70% of autopsied cases. In recent years, tetanus has been fatal in approximately 11% of reported cases. Cases most likely to be [[fatal]] are those occurring in persons 60 years of age and older (18%) and unvaccinated persons (22%). In about 20% of tetanus deaths, no obvious pathology is identified and death is attributed to the direct effects of tetanus toxin.
*Tetanus has been fatal in approximately 11% of reported cases
*Most commonly fatal cases found in:
**People of 60 years or older (approximately 18%)
**Unvaccinated people (approximately 22%)
*In about 20% of deaths, no obvious pathology is detected
**Death is attributed directly to the direct effects of tetanus toxin.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 13:49, 15 March 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural history

Complications

There are many complications associated with tetanus infection. Some of the complications are as follows:

Prognosis

Death in about 10-20% of cases, higher among older people.

In recent years:

  • Tetanus has been fatal in approximately 11% of reported cases
  • Most commonly fatal cases found in:
    • People of 60 years or older (approximately 18%)
    • Unvaccinated people (approximately 22%)
  • In about 20% of deaths, no obvious pathology is detected
    • Death is attributed directly to the direct effects of tetanus toxin.

References