TSPYL2: Difference between revisions

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{{Underlinked|date=June 2016}}
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{{Infobox_gene}}
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'''Testis-specific Y-encoded-like protein 2''' is a [[protein]] that in humans is encoded by the ''TSPYL2'' [[gene]].<ref name="pmid11318608">{{cite journal | vauthors = Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB | title = Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily | journal = Genomics | volume = 73 | issue = 2 | pages = 179–93 |date=Apr 2001 | pmid = 11318608 | pmc =  | doi = 10.1006/geno.2001.6505 }}</ref><ref name="pmid11395479">{{cite journal | vauthors = Chai Z, Sarcevic B, Mawson A, Toh BH | title = SET-related cell division autoantigen-1 (CDA1) arrests cell growth | journal = J Biol Chem | volume = 276 | issue = 36 | pages = 33665–74 |date=Sep 2001 | pmid = 11395479 | pmc =  | doi = 10.1074/jbc.M007681200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TSPYL2 TSPY-like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64061| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = TSPY-like 2
| HGNCid = 24358
| Symbol = TSPYL2
| AltSymbols =; CINAP; CDA1; CTCL; DENTT; HRIHFB2216; SE20-4
| OMIM = 300564
| ECnumber =
| Homologene = 11140
| MGIid = 106244
  | GeneAtlas_image1 = PBB_GE_TSPYL2_218012_at_tn.png
| Function = {{GNF_GO|id=GO:0000182 |text = rDNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005730 |text = nucleolus}}
| Process = {{GNF_GO|id=GO:0006334 |text = nucleosome assembly}} {{GNF_GO|id=GO:0008156 |text = negative regulation of DNA replication}} {{GNF_GO|id=GO:0009966 |text = regulation of signal transduction}} {{GNF_GO|id=GO:0030308 |text = negative regulation of cell growth}} {{GNF_GO|id=GO:0045786 |text = negative regulation of progression through cell cycle}} {{GNF_GO|id=GO:0045859 |text = regulation of protein kinase activity}} {{GNF_GO|id=GO:0051301 |text = cell division}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 64061
    | Hs_Ensembl = ENSG00000184205
    | Hs_RefseqProtein = XP_001128695
    | Hs_RefseqmRNA = XM_001128695
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 53128274
    | Hs_GenLoc_end = 53134447
    | Hs_Uniprot =   
    | Mm_EntrezGene = 52808
    | Mm_Ensembl = ENSMUSG00000041096
    | Mm_RefseqmRNA = NM_029836
    | Mm_RefseqProtein = NP_084112
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 147677568
    | Mm_GenLoc_end = 147683200
    | Mm_Uniprot = 
  }}
}}
'''TSPY-like 2''', also known as '''TSPYL2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TSPYL2 TSPY-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64061| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal | author=Eichmuller S, Usener D, Dummer R, ''et al.'' |title=Serological detection of cutaneous T-cell lymphoma-associated antigens. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 2 |pages= 629-34 |year= 2001 |pmid= 11149944 |doi= 10.1073/pnas.021386498 }}
*{{cite journal   |vauthors=Eichmuller S, Usener D, Dummer R, etal |title=Serological detection of cutaneous T-cell lymphoma-associated antigens. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 2 |pages= 629–34 |year= 2001 |pmid= 11149944 |doi= 10.1073/pnas.021386498 | pmc=14639 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal   |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }}
*{{cite journal | author=Ozbun LL, You L, Kiang S, ''et al.'' |title=Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily. |journal=Genomics |volume=73 |issue= 2 |pages= 179-93 |year= 2001 |pmid= 11318608 |doi= 10.1006/geno.2001.6505 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Chai Z, Sarcevic B, Mawson A, Toh BH |title=SET-related cell division autoantigen-1 (CDA1) arrests cell growth. |journal=J. Biol. Chem. |volume=276 |issue= 36 |pages= 33665-74 |year= 2001 |pmid= 11395479 |doi= 10.1074/jbc.M007681200 }}
*{{cite journal   |vauthors=Wang GS, Hong CJ, Yen TY, etal |title=Transcriptional modification by a CASK-interacting nucleosome assembly protein. |journal=Neuron |volume=42 |issue= 1 |pages= 113–28 |year= 2004 |pmid= 15066269 |doi=10.1016/S0896-6273(04)00139-4 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }}
*{{cite journal | author=Wang GS, Hong CJ, Yen TY, ''et al.'' |title=Transcriptional modification by a CASK-interacting nucleosome assembly protein. |journal=Neuron |volume=42 |issue= 1 |pages= 113-28 |year= 2004 |pmid= 15066269 |doi=  }}
*{{cite journal   |vauthors=Santama N, Ogg SC, Malekkou A, etal |title=Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus. |journal=J. Biol. Chem. |volume=280 |issue= 43 |pages= 36429–41 |year= 2006 |pmid= 16079131 |doi= 10.1074/jbc.M501982200 }}
*{{cite journal | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501 }}
*{{cite journal | author=Santama N, Ogg SC, Malekkou A, ''et al.'' |title=Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus. |journal=J. Biol. Chem. |volume=280 |issue= 43 |pages= 36429-41 |year= 2006 |pmid= 16079131 |doi= 10.1074/jbc.M501982200 }}
*{{cite journal   |vauthors=Lim J, Hao T, Shaw C, etal |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
*{{cite journal   |vauthors=Radke JR, Donald RG, Eibs A, etal |title=Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development. |journal=PLoS Pathog. |volume=2 |issue= 10 |pages= e105 |year= 2006 |pmid= 17069459 |doi= 10.1371/journal.ppat.0020105 | pmc=1626100 }}
*{{cite journal | author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal   |vauthors=Tu Y, Wu W, Wu T, etal |title=Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways. |journal=J. Biol. Chem. |volume=282 |issue= 16 |pages= 11722–31 |year= 2007 |pmid= 17317670 |doi= 10.1074/jbc.M609623200 }}
*{{cite journal | author=Radke JR, Donald RG, Eibs A, ''et al.'' |title=Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development. |journal=PLoS Pathog. |volume=2 |issue= 10 |pages= e105 |year= 2006 |pmid= 17069459 |doi= 10.1371/journal.ppat.0020105 }}
*{{cite journal | author=Tu Y, Wu W, Wu T, ''et al.'' |title=Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways. |journal=J. Biol. Chem. |volume=282 |issue= 16 |pages= 11722-31 |year= 2007 |pmid= 17317670 |doi= 10.1074/jbc.M609623200 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 12:22, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Testis-specific Y-encoded-like protein 2 is a protein that in humans is encoded by the TSPYL2 gene.[1][2][3]


References

  1. Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB (Apr 2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily". Genomics. 73 (2): 179–93. doi:10.1006/geno.2001.6505. PMID 11318608.
  2. Chai Z, Sarcevic B, Mawson A, Toh BH (Sep 2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth". J Biol Chem. 276 (36): 33665–74. doi:10.1074/jbc.M007681200. PMID 11395479.
  3. "Entrez Gene: TSPYL2 TSPY-like 2".

Further reading