View source for TRAM2

{{Infobox_gene}}
'''Translocating chain-associated membrane protein 2''' is a [[protein]] that in humans is encoded by the ''TRAM2'' [[gene]].<ref name="pmid7584044">{{cite journal | vauthors = Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S | title = Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1 | journal = DNA Res | volume = 1 | issue = 5 | pages = 223–9 |date=Dec 1995 | pmid = 7584044 | pmc =  | doi =10.1093/dnares/1.5.223  }}</ref><ref name="pmid10594243">{{cite journal | vauthors = Onuchic LF, Mrug M, Lakings AL, Muecher G, Becker J, Zerres K, Avner ED, Dixit M, Somlo S, Germino GG, Guay-Woodford LM | title = Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene | journal = Mamm Genome | volume = 10 | issue = 12 | pages = 1175–8 |date=Jan 2000 | pmid = 10594243 | pmc =  | doi =10.1007/s003359901186  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRAM2 translocation associated membrane protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9697| accessdate = }}</ref>

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{{PBB_Summary
| section_title = 
| summary_text = TRAM2 is a component of the [[translocon]], a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.<ref name="entrez">{{cite web | title = Entrez Gene: TRAM2 translocation associated membrane protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9697| accessdate = }}</ref>
}}

==References==
{{reflist}}

==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | vauthors=Sudo K, Chinen K, Nakamura Y |title=2058 expressed sequence tags (ESTs) from a human fetal lung cDNA library. |journal=Genomics |volume=24 |issue= 2 |pages= 276–9 |year= 1995 |pmid= 7698749 |doi= 10.1006/geno.1994.1616 }}
*{{cite journal   |vauthors=Hillier LD, Lennon G, Becker M, etal |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=10.1101/gr.6.9.807  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal   |vauthors=Mungall AJ, Palmer SA, Sims SK, etal |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal   |vauthors=Hsu LC, Liu S, Abedinpour F, etal |title=The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription. |journal=Mol. Cell. Biol. |volume=23 |issue= 23 |pages= 8773–85 |year= 2003 |pmid= 14612417 |doi=10.1128/MCB.23.23.8773-8785.2003  | pmc=262660  }}
*{{cite journal   |vauthors=Stefanovic B, Stefanovic L, Schnabl B, etal |title=TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. |journal=Mol. Cell. Biol. |volume=24 |issue= 4 |pages= 1758–68 |year= 2004 |pmid= 14749390 |doi=10.1128/MCB.24.4.1758-1768.2004  | pmc=344171  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129 }}
}}
{{refend}}

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