View source for TBC1D1

{{Infobox_gene}}
'''TBC1 domain family member 1''' is a [[protein]] that in humans is encoded by the ''TBC1D1'' [[gene]].<ref name="pmid10965142">{{cite journal | vauthors = White RA, Pasztor LM, Richardson PM, Zon LI | title = The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4 | journal = Cytogenet Cell Genet | volume = 89 | issue = 3-4 | pages = 272–5 |date=Sep 2000 | pmid = 10965142 | pmc =  | doi =10.1159/000015632  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23216| accessdate = }}</ref>

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{{PBB_Summary
| section_title = 
| summary_text = TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-[[amino acid]] [[TBC domain]] presumed to have a role in regulating [[cell growth]] and [[cell differentiation]]. These proteins share significant [[homology (biology)|homology]] with TRE2 (USP6; MIM 604334), [[Yeast expression platform|yeast]] Bub2, and [[CDC16]] (MIM 603461) (White et al., 2000).[supplied by OMIM]<ref name="entrez"/>
}}

==References==
{{reflist}}

==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal   |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99  }}
*{{cite journal  | vauthors=Roach WG, Chavez JA, Mîinea CP, Lienhard GE |title=Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1. |journal=Biochem. J. |volume=403 |issue= 2 |pages= 353–8 |year= 2007 |pmid= 17274760 |doi= 10.1042/BJ20061798  | pmc=1874243 }}
*{{cite journal   |vauthors=Stone S, Abkevich V, Russell DL, etal |title=TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition. |journal=Hum. Mol. Genet. |volume=15 |issue= 18 |pages= 2709–20 |year= 2006 |pmid= 16893906 |doi= 10.1093/hmg/ddl204 }}
*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal   |vauthors=Rush J, Moritz A, Lee KA, etal |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal   |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
*{{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104  | pmc=442148 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal   |vauthors=Kikuno R, Nagase T, Ishikawa K, etal |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=10.1093/dnares/6.3.197  }}
}}
{{refend}}

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