Smallpox: Difference between revisions

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__NOTOC__
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Infobox Disease |
{{Infobox Disease |
   Name        = Smallpox |
   Name        = Smallpox |
   Image      = smallpox.jpg |
   Image      = Smallpox-79.jpg |
   Caption    = A child infected with smallpox |
   Caption    = Maculopapular rash in smallpox.<SMALL><SMALL>''[http://phil.cdc.gov/phil/  Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL> |
}}
}}
__NOTOC__
{{About1|Smallpox virus}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{Smallpox}}
{{Smallpox}}
{{CMG}}
{{CMG}}; {{AE}} {{MJM}} {{JS}}
{{MJM}}


{{SK}} Variola.
{{SK}} Variola, Variola vera


==[[Smallpox overview|Overview]]==
==[[Smallpox overview|Overview]]==


==[[Smallpox historical perspective|Historical Perspective]]==
==[[Smallpox Historical Perspective|Historical Perspective]]==
[[Smallpox eradication|Eradication]] | [[Smallpox post eradication|Post-eradication]]
[[Smallpox eradication|Eradication]] | [[Smallpox post eradication|Post-Eradication]]


==[[Smallpox pathophysiology|Pathophysiology]]==
==[[Smallpox pathophysiology|Pathophysiology]]==
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==Diagnosis==
==Diagnosis==
[[Smallpox history and symptoms|History and Symptoms]] | [[Smallpox physical examination|Physical Examination]] | [[Smallpox laboratory tests|Laboratory Findings]]
[[Smallpox diagnostic criteria|Diagnostic Criteria]] | [[Smallpox history and symptoms|History and Symptoms]] | [[Smallpox physical examination|Physical Examination]] | [[Smallpox laboratory tests|Laboratory Findings]]


==Treatment==
==Treatment==
[[Smallpox medical therapy|Medical therapy]] | [[Smallpox primary prevention|Primary prevention]]  | [[Smallpox outbreak prevention|Outbreak prevention]] | [[Smallpox cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Smallpox future or investigational therapies|Future or Investigational Therapies]]
[[Smallpox medical therapy|Medical Therapy]] | [[Smallpox primary prevention|Primary Prevention]]  | [[Smallpox outbreak prevention|Outbreak Prevention]] | [[Smallpox cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Smallpox future or investigational therapies|Future or Investigational Therapies]]


==Case Studies==
==Case Studies==
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* [[Medieval demography]]
* [[Medieval demography]]
* [[Polio#Eradication|Polio]]
* [[Polio#Eradication|Polio]]
==Further Reading==
<div class="references-small" style="-moz-column-count:2; column-count:2;">
* Fenner, Frank, Henderson, D.A., Arita, Isao, Jezek, Zdenek, and Ladnyi, Ivan D.  [http://whqlibdoc.who.int/smallpox/9241561106.pdf ''Smallpox and its Eradication''].  World Health Organization (WHO), Geneva, Switzerland, 1988.  ISBN 92-4-156110-6.
* McNeill, William H. “''Plagues and Peoples''.” Bantam Doubleday Dell Publishing Group, Inc., New York, NY, 1976, ISBN 0-385-12122-9.
* Preston, Richard.  “''The Demon in the Freezer''”  Random House, New York, NY, 2002, ISBN 0-375-50856-2.
* [http://www.countway.harvard.edu/rarebooks/exhibits/waterhouse/ Catalog to the exhibit entitled “TO SLAY THE DEVOURING MONSTER: The Vaccination Experiments of Benjamin Waterhouse”] (2000). Hosted by the [http://www.countway.harvard.edu/rarebooks/exhibits.shtml Rare Books and Special Collections,  Francis A. Countway Library of Medicine]. Verified availability 2005-03-12.
* [http://content.nejm.org/cgi/content/full/348/5/460 A Different View of Smallpox and Vaccination Thomas Mack, M.D., M.P.H. NEJM Volume 348:460-463]
* Marie de Testa & Antoine Gautier, ''Une grande famille latine de l’Empire ottoman: les Timoni, medecins, drogmans et hommes d’église'', in Drogmans et diplomates européens auprès de la Porte ottomane, éditions ISIS, Istanbul, 2003, pp. 235-255.
* "Hugh Walker and North Carolina's 'Smallpox Currency' of 1779," R. Neil Fulghum. ''The Colonial Newsletter,'' a research journal of the [[American Numismatic Society]], New York. December 2005, pp.2895-2934.
* The Biomedical Scientist. September 2006, pp. 800-801.
</div>


==External Links==
==External Links==
===Disease information===
===Disease information===
* [http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp Smallpox Fact Sheet] from the [[Centers for Disease Control and Prevention|CDC]]
* [http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp Smallpox Fact Sheet] from the [[Centers for Disease Control and Prevention|CDC]]
* [http://www.bt.cdc.gov/agent/smallpox/index.asp CDC.gov]—‘Bioterrorism Agents > Smallpox Info for Specific Groups: What Everyone Should Know,’ [[Centers for Disease Control and Prevention|CDC]]
* [http://www.bt.cdc.gov/agent/smallpox/index.asp CDC.gov]—‘Bioterrorism Agents > Smallpox Info for Specific Groups: What Everyone Should Know,’ [[Centers for Disease Control and Prevention|CDC]]
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=== Smallpox in history ===
=== Smallpox in history ===
* [http://www.who.int/mediacentre/factsheets/smallpox/ WHO.int]—‘Smallpox: Historical significance,’ [[World Health Organization]] (WHO)
* [http://www.who.int/mediacentre/factsheets/smallpox/ WHO.int]—‘Smallpox: Historical significance,’ [[World Health Organization]] (WHO)


{{Viral diseases}}
==References==
{{reflist|2}}


{{Link FA|pl}}
[[Category:Disease]]
[[es:Viruela]]
[[fr:Variole]]
[[ja:天然痘]]
[[pt:Varíola]]
[[ro:Variolă]]
[[ru:Натуральная оспа]]
[[zh:天花]]
 
{{WH}}
{{WS}}


[[Category:Disease]]
[[Category:Infectious disease]]
[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Smallpox|Smallpox]]
[[Category:Smallpox|Smallpox]]
[[Category:Viral diseases]]
[[Category:Viral diseases]]
[[Category:Poxviruses]]
[[Category:Poxviruses]]
[[pl:Ospa prawdziwa]]
[[tr:Çiçek hastalığı]]

Latest revision as of 14:41, 11 June 2022

Smallpox
Maculopapular rash in smallpox.Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.[1]


This page is about clinical aspects of the disease.  For microbiologic aspects of the causative organism(s), see Smallpox virus.

For patient information click here

Smallpox Microchapters

Home

Patient Information

Overview

Historical Perspective

Eradication
Post-Eradication

Pathophysiology

Causes

Differentiating Smallpox from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Treatment

Medical Therapy

Primary Prevention

Outbreak Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case Studies

Smallpox On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Smallpox

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Smallpox

CDC on Smallpox

Smallpox in the news

Blogs on Smallpox

Directions to Hospitals Treating Smallpox

Risk calculators and risk factors for Smallpox

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Michael Maddaleni, B.S. João André Alves Silva, M.D. [2]

Synonyms and keywords: Variola, Variola vera

Overview

Historical Perspective

Eradication | Post-Eradication

Pathophysiology

Causes

Differentiating Smallpox from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings

Treatment

Medical Therapy | Primary Prevention | Outbreak Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Related Chapters

External Links

Disease information

General Information

Smallpox in history

References

  1. "Public Health Image Library (PHIL), Centers for Disease Control and Prevention".