Short QT syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Short QT syndrome(SQTS) is associated with an increased risk of atrial fibrillation, syncope and sudden death due to ventricular fibrillation.

Natural History

The symptoms of SQTS usually develop between the second and fourth decade of life and start with symptoms such as syncope and palpitations. Without treatment, the patient will develop symptoms of atrial fibrillation, which may eventually lead to cardiac arrest. The circumstances in which symptoms arise in SQTS patients are highly variable. According to a few studies, SQTS patients can be asymptomatic in a significant proportion of the study population and get diagnosed only with a strong familial predisposition[1].

References

  1. Rudic B, Schimpf R, Borggrefe M (2014). "Short QT Syndrome - Review of Diagnosis and Treatment". Arrhythm Electrophysiol Rev. 3 (2): 76–9. doi:10.15420/aer.2014.3.2.76. PMC 4711567. PMID 26835070.