Second degree AV block primary prevention: Difference between revisions

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* [[Pacemakers]] can usually provide adequate treatment of the symptoms of [[AV bloc]]k, no preventive or curative strategies are currently used in [[clinical]] practice.  
* [[Pacemakers]] can usually provide adequate treatment of the symptoms of [[AV bloc]]k, no preventive or curative strategies are currently used in [[clinical]] practice.  


* After implantation, [[patients]] require generator changes, which carry a particularly high risk of [[infection]] and resultant [[endocarditis]].<ref name="pmid16492298">{{cite journal |vauthors=Bloom H, Heeke B, Leon A, Mera F, Delurgio D, Beshai J, Langberg J |title=Renal insufficiency and the risk of infection from pacemaker or defibrillator surgery |journal=Pacing Clin Electrophysiol |volume=29 |issue=2 |pages=142–5 |date=February 2006 |pmid=16492298 |doi=10.1111/j.1540-8159.2006.00307.x |url=}}</ref>.
*
* Finally, independent of these [[procedural]] complications, successful [[pacemaker]] therapy has been associated with a worse [[prognosis]].<ref name="pmid22645234">{{cite journal |vauthors=Gang UJ, Hvelplund A, Pedersen S, Iversen A, Jøns C, Abildstrøm SZ, Haarbo J, Jensen JS, Thomsen PE |title=High-degree atrioventricular block complicating ST-segment elevation myocardial infarction in the era of primary percutaneous coronary intervention |journal=Europace |volume=14 |issue=11 |pages=1639–45 |date=November 2012 |pmid=22645234 |doi=10.1093/europace/eus161 |url=}}</ref><ref name="pmid626128">{{cite journal |vauthors=Simon AB, Zloto AE |title=Atrioventricular block: natural history after permanent ventricular pacing |journal=Am. J. Cardiol. |volume=41 |issue=3 |pages=500–7 |date=March 1978 |pmid=626128 |doi=10.1016/0002-9149(78)90006-1 |url=}}</ref>.
*A better understanding of the [[conditions]] associated with severe [[AV conduction ]] disease would enable the development of prevention strategies, ideally avoiding the [[pacemaker]]-associated complications and increased use of [[health care]] resources<ref name="pmid25912118">{{cite journal |vauthors=Bradshaw PJ, Stobie P, Knuiman MW, Briffa TG, Hobbs MS |title=Life expectancy after implantation of a first cardiac permanent pacemaker (1995-2008): A population-based study |journal=Int. J. Cardiol. |volume=190 |issue= |pages=42–6 |date=2015 |pmid=25912118 |doi=10.1016/j.ijcard.2015.04.099 |url=}}</ref>.
*No previous study, to our knowledge, has reported the population-based characteristics associated with incident AV block.
*No previous study, to our knowledge, has reported the population-based characteristics associated with incident AV block.
* Atrioventricular block is associated with multiple known [[cardiovascular]] [[risk factors]] and [[conditions]].  
* Atrioventricular block is associated with multiple known [[cardiovascular]] [[risk factors]] and [[conditions]].  

Revision as of 05:34, 11 July 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Effective measures for primary prevention of atrioventricular block include treatment of hypertension and maintenance of normal blood glucose levels. Atrioventricular (AV) block is a common reason for pacemaker implantation, and the number of pacemaker implantations is increasing. Atrioventricular block most commonly occurs in the absence of significant cardiac disease and is generally attributed to idiopathic fibrosis of the conduction system. By definition, the cause of that fibrosis remains unknown without primary prevention strategy.

Primary prevention




  • Pacemaker implantations as a treatment for atrioventricular (AV) block are increasing worldwide. Prevention strategies for AV block are lacking because modifiable risk factors have not yet been identified[1][2][3].
  • Pacemakers can usually provide adequate treatment of the symptoms of AV block, no preventive or curative strategies are currently used in clinical practice.

References

  1. Kerola T, Eranti A, Aro AL, Haukilahti MA, Holkeri A, Junttila MJ, Kenttä TV, Rissanen H, Vittinghoff E, Knekt P, Heliövaara M, Huikuri HV, Marcus GM (May 2019). "Risk Factors Associated With Atrioventricular Block". JAMA Netw Open. 2 (5): e194176. doi:10.1001/jamanetworkopen.2019.4176. PMC 6632153 Check |pmc= value (help). PMID 31125096.
  2. Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L (2004). "Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study". Lancet. 364 (9438): 937–52. doi:10.1016/S0140-6736(04)17018-9. PMID 15364185.
  3. LEV M (November 1964). "ANATOMIC BASIS FOR ATRIOVENTRICULAR BLOCK". Am. J. Med. 37: 742–8. doi:10.1016/0002-9343(64)90022-1. PMID 14237429.
  4. Epstein AE, Dimarco JP, Ellenbogen KA, Estes NA, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO (June 2008). "ACC/AHA/HRS 2008 guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: executive summary". Heart Rhythm. 5 (6): 934–55. doi:10.1016/j.hrthm.2008.04.015. PMID 18534377.


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