Sandbox sowminya: Difference between revisions

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|-
| style="padding: 5px 5px; background: #F5F5F5;" | I
| style="padding: 5px 5px; background: #F5F5F5;" | I
| style="padding: 5px 5px; background: #F5F5F5;" | (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | * (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
|-
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| style="padding: 5px 5px; background: #F5F5F5;" | II
| style="padding: 5px 5px; background: #F5F5F5;" | II
| style="padding: 5px 5px; background: #F5F5F5;" | (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | * (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
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|-
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| style="padding: 5px 5px; background: #F5F5F5;" | III
| style="padding: 5px 5px; background: #F5F5F5;" | III
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]] <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" |  
* (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]] <BR>  
* (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR>  
* ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR>  
* ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" | IV
| style="padding: 5px 5px; background: #F5F5F5;" | IV
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]  <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]  <BR>
* (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR>  
* ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR>  
* ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
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|-
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| style="padding: 5px 5px; background: #F5F5F5;" | Recurrence
| style="padding: 5px 5px; background: #F5F5F5;" | Recurrence
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]  <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]  <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]  <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]] <BR> (GDP)[[Gemcitabine]] {{and}} [[Dexamethasone]] {{and}} [[Cisplatin]] <BR> (CBV) [[Cyclophosphamide]] {{and}} [[Carmustine]] {{and}} [[Etoposide]]  <BR> (BEAM) [[Carmustine]] {{and}} [[Etoposide]] {{and}} [[Cytarabine]] {{and}} [[Melphalan]]
| style="padding: 5px 5px; background: #F5F5F5;" |  
* (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]  <BR>  
* (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]  <BR>  
* ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]  <BR>  
* ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]] <BR>  
* (GDP)[[Gemcitabine]] {{and}} [[Dexamethasone]] {{and}} [[Cisplatin]] <BR>  
* (CBV) [[Cyclophosphamide]] {{and}} [[Carmustine]] {{and}} [[Etoposide]]  <BR>  
* (BEAM) [[Carmustine]] {{and}} [[Etoposide]] {{and}} [[Cytarabine]] {{and}} [[Melphalan]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | Stem cell transplant may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | Stem cell transplant may be offered
|}
|}

Revision as of 15:46, 11 September 2015

 
 
 
 
 
 
 
 
 
B-cell neoplasms
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CD5+
 
 
 
 
 
 
 
CD5-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CCND1+
 
 
 
CCND1-
 
 
 
 
DLBCL
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pleomorphic MCL
 
 
 
DLBCL, NOS CD5+
 
CD10+
 
 
 
 
 
 
 
CD10-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BCL6+ IRF4/MUM1-
 
BCL6+ IRF4/MUM1+
 
BCL6- IRF4/MUM1+
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
Non-GCB
 
Post-GCB
 
 



Use of Immunophenotyping/Genetic Testing in Differential Diagnosis of Mature B-Cell and NK/T-Cell Neoplasms


 
 
 
 
 
 
 
 
 
B-cell neoplasms
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CD5+
 
 
 
 
 
 
 
CD5-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CCND1+
 
 
 
CCND1-
 
 
 
 
DLBCL
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pleomorphic MCL
 
 
 
DLBCL, NOS CD5+
 
CD10+
 
 
 
 
 
 
 
CD10-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BCL6+ IRF4/MUM1-
 
BCL6+ IRF4/MUM1+
 
BCL6- IRF4/MUM1+
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
Non-GCB
 
Post-GCB
 
 
Revised staging system for primary nodal lymphomas (Lugano classification)
Stage Chemotherapy Radiotherapy Stem cell transplant
I & II
I * (ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine External beam radiation therapy may be offered
II * (ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine External beam radiation therapy may be offered
III & IV
III External beam radiation therapy may be offered
IV
Recurrent disease
Recurrence External beam radiation therapy may be offered Stem cell transplant may be offered
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