Sandbox sowminya: Difference between revisions

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| style="padding: 5px 5px; background: #F5F5F5;" | III
| style="padding: 5px 5px; background: #F5F5F5;" | III
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]] <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
(''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]  
([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
|-
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| style="padding: 5px 5px; background: #F5F5F5;" | IV
| style="padding: 5px 5px; background: #F5F5F5;" | IV
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]] <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]] <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
(''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]  
([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" |
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| style="padding: 5px 5px; background: #F5F5F5;" | Recurrence
| style="padding: 5px 5px; background: #F5F5F5;" | Recurrence
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]]
| style="padding: 5px 5px; background: #F5F5F5;" | (MOPP) [[Mechlorethamine]] {{and}} [[Oncovin]] {{and}} [[Prednisone]] {{and}} [[Procarbazine]] <BR> (''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]] <BR> ([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]  <BR> ([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]] <BR> (GDP)[[Gemcitabine]] {{and}} [[Dexamethasone]] {{and}} [[Cisplatin]] <BR> (CBV) [[Cyclophosphamide]] {{and}} [[Carmustine]] {{and}} [[Etoposide]]  <BR> (BEAM) [[Carmustine]] {{and}} [[Etoposide]] {{and}} [[Cytarabine]] {{and}} [[Melphalan]]
(''[[ABVD]]'') [[Adriamycin]] {{and}} [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Dacarbazine]]
 
([[Stanford V]]) [[Adriamycin]] {{and}}  [[Bleomycin]] {{and}} [[Vinblastine]] {{and}} [[Vincristine]] {{and}} [[Mechlorethamine]] {{and}} [[Etoposide]] {{and}} [[Prednisone]]
   
([[BEACOPP]]) [[Bleomycin]] {{and}} [[Etoposide]] {{and}} [[Adriamycin]] {{and}} [[Cyclophosphamide]] {{and}} [[Oncovin]] {{and}} [[Procarbazine]] {{and}} [[Prednisone]]
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" | External beam radiation therapy may be offered
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Stem cell transplant may be offered
|}
|}

Revision as of 15:27, 11 September 2015

 
 
 
 
 
 
 
 
 
B-cell neoplasms
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CD5+
 
 
 
 
 
 
 
CD5-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CCND1+
 
 
 
CCND1-
 
 
 
 
DLBCL
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pleomorphic MCL
 
 
 
DLBCL, NOS CD5+
 
CD10+
 
 
 
 
 
 
 
CD10-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BCL6+ IRF4/MUM1-
 
BCL6+ IRF4/MUM1+
 
BCL6- IRF4/MUM1+
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
Non-GCB
 
Post-GCB
 
 



Use of Immunophenotyping/Genetic Testing in Differential Diagnosis of Mature B-Cell and NK/T-Cell Neoplasms


 
 
 
 
 
 
 
 
 
B-cell neoplasms
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CD5+
 
 
 
 
 
 
 
CD5-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CCND1+
 
 
 
CCND1-
 
 
 
 
DLBCL
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pleomorphic MCL
 
 
 
DLBCL, NOS CD5+
 
CD10+
 
 
 
 
 
 
 
CD10-
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BCL6+ IRF4/MUM1-
 
BCL6+ IRF4/MUM1+
 
BCL6- IRF4/MUM1+
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DLBCL, NOS GCB type
 
Non-GCB
 
Post-GCB
 
 
Revised staging system for primary nodal lymphomas (Lugano classification)
Stage Chemotherapy Radiotherapy Stem cell transplant
I & II
I (ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine External beam radiation therapy may be offered
II (ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine External beam radiation therapy may be offered
III & IV
III (MOPP) Mechlorethamine AND Oncovin AND Prednisone AND Procarbazine
(ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine
(Stanford V) Adriamycin AND Bleomycin AND Vinblastine AND Vincristine AND Mechlorethamine AND Etoposide AND Prednisone
(BEACOPP) Bleomycin AND Etoposide AND Adriamycin AND Cyclophosphamide AND Oncovin AND Procarbazine AND Prednisone 		External beam radiation therapy may be offered
IV (MOPP) Mechlorethamine AND Oncovin AND Prednisone AND Procarbazine
(ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine
(Stanford V) Adriamycin AND Bleomycin AND Vinblastine AND Vincristine AND Mechlorethamine AND Etoposide AND Prednisone
(BEACOPP) Bleomycin AND Etoposide AND Adriamycin AND Cyclophosphamide AND Oncovin AND Procarbazine AND Prednisone
Recurrent disease
Recurrence (MOPP) Mechlorethamine AND Oncovin AND Prednisone AND Procarbazine
(ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine
(Stanford V) Adriamycin AND Bleomycin AND Vinblastine AND Vincristine AND Mechlorethamine AND Etoposide AND Prednisone
(BEACOPP) Bleomycin AND Etoposide AND Adriamycin AND Cyclophosphamide AND Oncovin AND Procarbazine AND Prednisone
(GDP)Gemcitabine AND Dexamethasone AND Cisplatin
(CBV) Cyclophosphamide AND Carmustine AND Etoposide
(BEAM) Carmustine AND Etoposide AND Cytarabine AND Melphalan 		External beam radiation therapy may be offered Stem cell transplant may be offered
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