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Acute Kidney Injury




Overview


Acute kidney injury (AKI) or acute renal failure (ARF), is characterized by a rapid reduction of the renal filtration function, which is identified by a rise in serum creatinine concentration.

Historical Perspective




Classification


  • Acute kidney injury is classified into three main groups:
    1. Prerenal
    2. Renal
    3. Postrenal
lab findings in AKI
Type UOsm UNa FeNa BUN/Cr
Prerenal >500 <10 <1% >20
Renal <350 >20 >2% <10-15
Postrenal <350 >40 >4% >20


Type UOsm UNa FeNa BUN/Cr
Prerenal >500 <10 <1% >20
Renal <350 >20 >2% <10-15
Postrenal <350 >40 >4% >20
  • Acute kidney injury is classified into three main groups:
    • Prerenal
    • Renal
    • Postrenal

 
 
 
 
 
 
 
 
AKI
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Prerenal
 
 
 
 
Renal
 
 
 
 
Postrenal
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Nephrotoxicity
• contrast dyes
• Rhabdomyolysis
 
 
 
• Ischemia
• Hypoxia
• Hypotension
 
 
 
• Inflammation
• Sepsis
• Infection