Sandbox:Nasrin: Difference between revisions
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Acute kidney injury (AKI) or acute renal failure (ARF), is characterized by a rapid reduction of the renal filtration function, which is identified by a rise in serum creatinine concentration. <br><br>'''<font size="3">Historical Perspective</font>''' | Acute kidney injury (AKI) or acute renal failure (ARF), is characterized by a rapid reduction of the renal filtration function, which is identified by a rise in serum creatinine concentration.<ref name="pmid15232604">{{cite journal| author=Schrier RW, Wang W, Poole B, Mitra A| title=Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. | journal=J Clin Invest | year= 2004 | volume= 114 | issue= 1 | pages= 5-14 | pmid=15232604 | doi=10.1172/JCI22353 | pmc=437979 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15232604 }} </ref> <br><br>'''<font size="3">Historical Perspective</font>''' | ||
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'''<font size="3">Classification</font>''' | '''<font size="3">Classification</font>''' | ||
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{{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }} | {{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }} | ||
{{Family tree| | |D01 | | | | D02 | | | | D03| | D01=•[[Nephrotoxicity]]<br>• contrast dyes<br>• [[Rhabdomyolysis]]<br>|D02=• [[Ischemia]]<br>• [[Hypoxia]]<br>• Hypotension<br>|D03=• [[Inflammation]]<br>• [[Sepsis]]<br>• [[Infection]]<br>}} | {{Family tree| | |D01 | | | | D02 | | | | D03| | D01=•[[Nephrotoxicity]]<br>• contrast dyes<br>• [[Rhabdomyolysis]]<br>|D02=• [[Ischemia]]<br>• [[Hypoxia]]<br>• Hypotension<br>|D03=• [[Inflammation]]<br>• [[Sepsis]]<br>• [[Infection]]<br>}} | ||
{{Family tree/end}} | {{Family tree/end}}<br><br><br> | ||
[[File:Etiologies of AKI.jpg]] | |||
Revision as of 15:50, 19 May 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nasrin Nikravangolsefid, MD-MPH [2]
Overview
Acute kidney injury (AKI) or acute renal failure (ARF), is characterized by a rapid reduction of the renal filtration function, which is identified by a rise in serum creatinine concentration.[1]
Historical Perspective
Classification
- Acute kidney injury is classified into three main groups:
1. Prerenal
2. Renal
3. Postrenal
| Type | UOsm | UNa | FeNa | BUN/Cr |
|---|---|---|---|---|
| Prerenal | >500 | <10 | <1% | >20 |
| Renal | <350 | >20 | >2% | <10-15 |
| Postrenal | <350 | >40 | >4% | >20 |
| Type | UOsm | UNa | FeNa | BUN/Cr |
|---|---|---|---|---|
| Prerenal | >500 | <10 | <1% | >20 |
| Renal | <350 | >20 | >2% | <10-15 |
| Postrenal | <350 | >40 | >4% | >20 |
| AKI | |||||||||||||||||||||||||||||||||||
| Prerenal | Renal | Postrenal | |||||||||||||||||||||||||||||||||
| •Nephrotoxicity • contrast dyes • Rhabdomyolysis | • Ischemia • Hypoxia • Hypotension | • Inflammation • Sepsis • Infection | |||||||||||||||||||||||||||||||||
- ↑ Schrier RW, Wang W, Poole B, Mitra A (2004). "Acute renal failure: definitions, diagnosis, pathogenesis, and therapy". J Clin Invest. 114 (1): 5–14. doi:10.1172/JCI22353. PMC 437979. PMID 15232604.