Sandbox/00002

Symptoms & Signs ❑ Altered mental status ❑ Clammy skin ± cyanosis ❑ Hypotension (MAP <70 mmHg) ❑ Oliguria (urine output <0.5 mL/kg/h) ❑ Tachycardia (heart rate >100 bpm)

Shock

Ventilate ❑ Intubation with mechanical ventilation Infuse ❑ Normal saline 500–1000 mL every 10–15 minutes (for septic and hypovolemic shock) ❑ Normal saline 100–200 mL boluses (for cardiogenic shock) Pump ❑ Norepinephrine 0.1–2.0 μg/kg/min

Immediate Goals ❑ MAP >60–65 mmHg ❑ CVP 8–12 mmHg ❑ PCWP 12–15 mmHg ❑ CI >2.1 L/min/m2 ❑ Hemoglobin >7–9 g/dL ❑ SaO2 >90%–92% ❑ MVO2 >60% ❑ SCVO2 >70% ❑ Lactate <2.2 mM/L ❑ Urine output >0.5 mL/kg/h