ST elevation myocardial infarction anticoagulant and antithrombotic therapy: Difference between revisions
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==Sites of Action of Antithrombins== | ==Sites of Action of Antithrombins== | ||
The majority of established and investigational antithrombins <ref name="pmid16953267">{{cite journal |author=Weitz JI |title=Emerging anticoagulants for the treatment of venous thromboembolism |journal=Thromb. Haemost. |volume=96 |issue=3 |pages=274–84 |year=2006 |month=September |pmid=16953267 |doi=10.1160/TH06-05-0234 |url=http://www.schattauer.de/index.php?id=1268&pii=th06090274&no_cache=1}}</ref> target two factors in the coagulation cascade: Factor Xa and Factor II. | |||
===Parenteral Drugs Targeting Factor Xa=== | ===Parenteral Drugs Targeting Factor Xa=== | ||
[[Fondaparinux]] | [[Fondaparinux]] |
Revision as of 23:53, 21 April 2009
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Sites of Action of Antithrombins
The majority of established and investigational antithrombins [1] target two factors in the coagulation cascade: Factor Xa and Factor II.
Parenteral Drugs Targeting Factor Xa
Idraparinux
Oral Drugs Targeting Factor Xa
Rivaroxaban
Apixaban
LY517717
YM150
DU-176b
PRT-054021
References
- ↑ Weitz JI (2006). "Emerging anticoagulants for the treatment of venous thromboembolism". Thromb. Haemost. 96 (3): 274–84. doi:10.1160/TH06-05-0234. PMID 16953267. Unknown parameter
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ignored (help)