SNAP29

Synaptosomal-associated protein, 29kDa
Identifiers
Symbols	SNAP29 ; CEDNIK; FLJ21051; SNAP-29
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3512
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SNAP29 218327 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Synaptosomal-associated protein, 29kDa, also known as SNAP29, is a human gene.

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.

Further reading

• Steegmaier M, Yang B, Yoo JS; et al. (1999). "Three novel proteins of the syntaxin/SNAP-25 family". J. Biol. Chem. 273 (51): 34171–9. PMID 9852078.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wong SH, Xu Y, Zhang T; et al. (1999). "GS32, a novel Golgi SNARE of 32 kDa, interacts preferentially with syntaxin 6". Mol. Biol. Cell. 10 (1): 119–34. PMID 9880331.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scales SJ, Chen YA, Yoo BY; et al. (2000). "SNAREs contribute to the specificity of membrane fusion". Neuron. 26 (2): 457–64. PMID 10839363.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rotem-Yehudar R, Galperin E, Horowitz M (2001). "Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29". J. Biol. Chem. 276 (35): 33054–60. doi:10.1074/jbc.M009913200. PMID 11423532.CS1 maint: Multiple names: authors list (link)
• Hohenstein AC, Roche PA (2001). "SNAP-29 is a promiscuous syntaxin-binding SNARE". Biochem. Biophys. Res. Commun. 285 (2): 167–71. doi:10.1006/bbrc.2001.5141. PMID 11444821.
• Su Q, Mochida S, Tian JH; et al. (2002). "SNAP-29: a general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission". Proc. Natl. Acad. Sci. U.S.A. 98 (24): 14038–43. doi:10.1073/pnas.251532398. PMID 11707603.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinez-Arca S, Rudge R, Vacca M; et al. (2003). "A dual mechanism controlling the localization and function of exocytic v-SNAREs". Proc. Natl. Acad. Sci. U.S.A. 100 (15): 9011–6. doi:10.1073/pnas.1431910100. PMID 12853575.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu Y, Shi H, Wei S; et al. (2005). "Mutually exclusive interactions of EHD1 with GS32 and syndapin II". Mol. Membr. Biol. 21 (4): 269–77. doi:10.1080/09687680410001716871. PMID 15371016.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Collins JE, Wright CL, Edwards CA; et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pan PY, Cai Q, Lin L; et al. (2005). "SNAP-29-mediated modulation of synaptic transmission in cultured hippocampal neurons". J. Biol. Chem. 280 (27): 25769–79. doi:10.1074/jbc.M502356200. PMID 15890653.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sprecher E, Ishida-Yamamoto A, Mizrahi-Koren M; et al. (2005). "A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma". Am. J. Hum. Genet. 77 (2): 242–51. doi:10.1086/432556. PMID 15968592.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carroll JS, Liu XS, Brodsky AS; et al. (2005). "Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1". Cell. 122 (1): 33–43. doi:10.1016/j.cell.2005.05.008. PMID 16009131.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)