SFRS6: Difference between revisions
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* {{cite journal | vauthors = Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA | title = A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer | journal = Molecular and Cellular Biology | volume = 15 | issue = 9 | pages = 4898–907 | date = September 1995 | pmid = 7651409 | pmc = 230736 | doi = }} | * {{cite journal | vauthors = Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA | title = A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer | journal = Molecular and Cellular Biology | volume = 15 | issue = 9 | pages = 4898–907 | date = September 1995 | pmid = 7651409 | pmc = 230736 | doi = }} | ||
* {{cite journal | vauthors = Gui JF, Lane WS, Fu XD | title = A serine kinase regulates intracellular localization of splicing factors in the cell cycle | journal = Nature | volume = 369 | issue = 6482 | pages = 678–82 | date = June 1994 | pmid = 8208298 | doi = 10.1038/369678a0 }} | * {{cite journal | vauthors = Gui JF, Lane WS, Fu XD | title = A serine kinase regulates intracellular localization of splicing factors in the cell cycle | journal = Nature | volume = 369 | issue = 6482 | pages = 678–82 | date = June 1994 | pmid = 8208298 | doi = 10.1038/369678a0 }} | ||
* {{cite journal | vauthors = Nagel RJ, Lancaster AM, Zahler AM | title = Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55 | journal = | * {{cite journal | vauthors = Nagel RJ, Lancaster AM, Zahler AM | title = Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55 | journal = RNA | volume = 4 | issue = 1 | pages = 11–23 | date = January 1998 | pmid = 9436904 | pmc = 1369592 | doi = }} | ||
* {{cite journal | vauthors = Liu HX, Zhang M, Krainer AR | title = Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins | journal = Genes & Development | volume = 12 | issue = 13 | pages = 1998–2012 | date = July 1998 | pmid = 9649504 | pmc = 316967 | doi = 10.1101/gad.12.13.1998 }} | * {{cite journal | vauthors = Liu HX, Zhang M, Krainer AR | title = Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins | journal = Genes & Development | volume = 12 | issue = 13 | pages = 1998–2012 | date = July 1998 | pmid = 9649504 | pmc = 316967 | doi = 10.1101/gad.12.13.1998 }} | ||
* {{cite journal | vauthors = Lemaire R, Winne A, Sarkissian M, Lafyatis R | title = SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation | journal = European Journal of Immunology | volume = 29 | issue = 3 | pages = 823–37 | date = March 1999 | pmid = 10092085 | doi = 10.1002/(SICI)1521-4141(199903)29:03<823::AID-IMMU823>3.0.CO;2-C }} | * {{cite journal | vauthors = Lemaire R, Winne A, Sarkissian M, Lafyatis R | title = SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation | journal = European Journal of Immunology | volume = 29 | issue = 3 | pages = 823–37 | date = March 1999 | pmid = 10092085 | doi = 10.1002/(SICI)1521-4141(199903)29:03<823::AID-IMMU823>3.0.CO;2-C }} | ||
| Line 28: | Line 28: | ||
* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }} | * {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }} | ||
{{refend}} | {{refend}} | ||
{{gene-20-stub}} | {{gene-20-stub}} | ||
Latest revision as of 07:15, 10 January 2019
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Splicing factor, arginine/serine-rich 6 is a protein that in humans is encoded by the SFRS6 gene.[1][2]
Function
The protein encoded by this gene is involved in mRNA splicing and may play a role in site selection in alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.[2]
References
- ↑ Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR (September 1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". The EMBO Journal. 14 (17): 4336–49. PMC 394518. PMID 7556075.
- ↑ 2.0 2.1 "Entrez Gene: SFRS6 splicing factor, arginine/serine-rich 6".
Further reading
- Zahler AM, Lane WS, Stolk JA, Roth MB (May 1992). "SR proteins: a conserved family of pre-mRNA splicing factors". Genes & Development. 6 (5): 837–47. doi:10.1101/gad.6.5.837. PMID 1577277.
- Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA (September 1995). "A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer". Molecular and Cellular Biology. 15 (9): 4898–907. PMC 230736. PMID 7651409.
- Gui JF, Lane WS, Fu XD (June 1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle". Nature. 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
- Nagel RJ, Lancaster AM, Zahler AM (January 1998). "Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55". RNA. 4 (1): 11–23. PMC 1369592. PMID 9436904.
- Liu HX, Zhang M, Krainer AR (July 1998). "Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins". Genes & Development. 12 (13): 1998–2012. doi:10.1101/gad.12.13.1998. PMC 316967. PMID 9649504.
- Lemaire R, Winne A, Sarkissian M, Lafyatis R (March 1999). "SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation". European Journal of Immunology. 29 (3): 823–37. doi:10.1002/(SICI)1521-4141(199903)29:03<823::AID-IMMU823>3.0.CO;2-C. PMID 10092085.
- Paillard F (May 1999). "A novel soluble chimera for the treatment of familial hypercholesterolemia". Human Gene Therapy. 10 (7): 1093–4. doi:10.1089/10430349950018085. PMID 10340541.
- Barnard DC, Patton JG (May 2000). "Identification and characterization of a novel serine-arginine-rich splicing regulatory protein". Molecular and Cellular Biology. 20 (9): 3049–57. doi:10.1128/MCB.20.9.3049-3057.2000. PMC 85584. PMID 10757789.
- Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM (August 2000). "Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1". Molecular Cell. 6 (2): 307–16. doi:10.1016/S1097-2765(00)00031-9. PMID 10983978.
- Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW (August 2001). "A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20". Genomics. 76 (1–3): 45–57. doi:10.1006/geno.2001.6584. PMID 11549316.
- Tran Q, Coleman TP, Roesser JR (January 2003). "Human transformer 2beta and SRp55 interact with a calcitonin-specific splice enhancer". Biochimica et Biophysica Acta. 1625 (2): 141–52. doi:10.1016/S0167-4781(02)00600-0. PMID 12531473.
- Tran Q, Roesser JR (February 2003). "SRp55 is a regulator of calcitonin/CGRP alternative RNA splicing". Biochemistry. 42 (4): 951–7. doi:10.1021/bi026753a. PMID 12549914.
- Lai MC, Lin RI, Tarn WY (May 2003). "Differential effects of hyperphosphorylation on splicing factor SRp55". The Biochemical Journal. 371 (Pt 3): 937–45. doi:10.1042/BJ20021827. PMC 1223332. PMID 12549978.
- Pind MT, Watson PH (May 2003). "SR protein expression and CD44 splicing pattern in human breast tumours". Breast Cancer Research and Treatment. 79 (1): 75–82. doi:10.1023/A:1023338718974. PMID 12779084.
- Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG (November 2003). "Regulation of alternative splicing by SRrp86 and its interacting proteins". Molecular and Cellular Biology. 23 (21): 7437–47. doi:10.1128/MCB.23.21.7437-7447.2003. PMC 207616. PMID 14559993.
- Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
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