SEMA4D
| Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
File:PBB Protein SEMA4D image.jpg PDB rendering based on 1olz. | |||||||||||||
| |||||||||||||
| Identifiers | |||||||||||||
| Symbols | SEMA4D ; CD100; M-sema G; M-sema-G; SEMAJ; coll-4 | ||||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 21282 | ||||||||||||
| |||||||||||||
| RNA expression pattern | |||||||||||||
| File:PBB GE SEMA4D 203528 at tn.png | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Template:GNF Ortholog box | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | n/a | n/a | |||||||||||
| Ensembl | n/a | n/a | |||||||||||
| UniProt | n/a | n/a | |||||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||||
| RefSeq (protein) | n/a | n/a | |||||||||||
| Location (UCSC) | n/a | n/a | |||||||||||
| PubMed search | n/a | n/a | |||||||||||
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D) also known as CD100 (Cluster of Differentiation 100), is a human gene.[1]
See also
References
Further reading
- Bougeret C, Mansur IG, Dastot H; et al. (1992). "Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation". J. Immunol. 148 (2): 318–23. PMID 1530858.
- Hall KT, Boumsell L, Schultze JL; et al. (1996). "Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation". Proc. Natl. Acad. Sci. U.S.A. 93 (21): 11780–5. PMID 8876214.
- Herold C, Elhabazi A, Bismuth G; et al. (1997). "CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion". J. Immunol. 157 (12): 5262–8. PMID 8955171.
- Furuyama T, Inagaki S, Kosugi A; et al. (1997). "Identification of a novel transmembrane semaphorin expressed on lymphocytes". J. Biol. Chem. 271 (52): 33376–81. PMID 8969198.
- Tamagnone L, Artigiani S, Chen H; et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell. 99 (1): 71–80. PMID 10520995.
- Kumanogoh A, Watanabe C, Lee I; et al. (2001). "Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling". Immunity. 13 (5): 621–31. PMID 11114375.
- Elhabazi A, Delaire S, Bensussan A; et al. (2001). "Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis". J. Immunol. 166 (7): 4341–7. PMID 11254687.
- Delaire S, Billard C, Tordjman R; et al. (2001). "Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration". J. Immunol. 166 (7): 4348–54. PMID 11254688.
- Vikis HG, Li W, Guan KL (2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding". Genes Dev. 16 (7): 836–45. doi:10.1101/gad.966402. PMID 11937491.
- Granziero L, Circosta P, Scielzo C; et al. (2003). "CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes". Blood. 101 (5): 1962–9. doi:10.1182/blood-2002-05-1339. PMID 12406905.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Izmailova E, Bertley FM, Huang Q; et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
- Ishida I, Kumanogoh A, Suzuki K; et al. (2004). "Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses". Int. Immunol. 15 (8): 1027–34. PMID 12882840.
- Love CA, Harlos K, Mavaddat N; et al. (2003). "The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D". Nat. Struct. Biol. 10 (10): 843–8. doi:10.1038/nsb977. PMID 12958590.
- Giraudon P, Vincent P, Vuaillat C; et al. (2004). "Semaphorin CD100 from activated T lymphocytes induces process extension collapse in oligodendrocytes and death of immature neural cells". J. Immunol. 172 (2): 1246–55. PMID 14707103.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Deaglio S, Vaisitti T, Bergui L; et al. (2005). "CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival". Blood. 105 (8): 3042–50. doi:10.1182/blood-2004-10-3873. PMID 15613544.
- Conrotto P, Valdembri D, Corso S; et al. (2005). "Sema4D induces angiogenesis through Met recruitment by Plexin B1". Blood. 105 (11): 4321–9. doi:10.1182/blood-2004-07-2885. PMID 15632204.
- Basile JR, Afkhami T, Gutkind JS (2005). "Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway". Mol. Cell. Biol. 25 (16): 6889–98. doi:10.1128/MCB.25.16.6889-6898.2005. PMID 16055703.
- Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach". Mol. Cell Proteomics. 5 (2): 226–33. doi:10.1074/mcp.M500324-MCP200. PMID 16263699.
External links
- SEMA4D+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
| Stub icon | This membrane protein–related article is a stub. You can help Wikipedia by expanding it. |
