Rhinitis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]

Overview

Natural History, Complications, Prognosis

Natural history

Rhinitis is a very common disease, and it is sometimes mistakenly viewed as a trivial disease.[1][2] Symptoms usually resolve within 7-10 days of onset.[2] Allergic rhinitis rarely occurs in isolation, it is a product of a genetic predisposition, epigenetic events, and environmental exposures, and it is frequently associated with other forms of atopy such as eczema, asthma, and allergic rhinoconjunctivitis.[3][4] Nonallergic rhinitis is also associated with asthma.[5][6] Frequent extension of rhinitis (especially infectious rhinitis) into the sinuses also occur, resulting in rhinosinusitis.[7][2] Remissions are more likely to occur in children with nonallergic rhinitis, those with allergic rhinitis tend to have a more persistent disease.[5] Remissions occur in up to 73% of four year old children with nonallergic rhinitis by the age of eight years.[5] Rhinitis is a significant cause of loss school and work days, and it constitutes a huge financial burden for the society. Untreated/poorly treated chronic rhinitis is associated with a diminished quality of life, disordered sleep, impaired work performance, and several other comorbidities.[2][3]


References

  1. Wallace DV, Dykewicz MS, Bernstein DI, Blessing-Moore J, Cox L, Khan DA; et al. (2008). "The diagnosis and management of rhinitis: an updated practice parameter". J Allergy Clin Immunol. 122 (2 Suppl): S1–84. doi:10.1016/j.jaci.2008.06.003. PMID 18662584.
  2. 2.0 2.1 2.2 2.3 Romeo, Jonathan; Dykewicz, Mark (2014). "Chapter 9:Differential Diagnosis of Rhinitis and Rhinosinusitis". Diseases of the Sinuses. Springer New York. pp. 133–152. ISBN 978-1-4939-0265-1.
  3. 3.0 3.1 Sacre Hazouri JA (2006). "[Allergic rhinitis. Coexistent diseases and complications. A review and analysis]". Rev Alerg Mex. 53 (1): 9–29. PMID 16634358.
  4. Mims JW (2014). "Epidemiology of allergic rhinitis". Int Forum Allergy Rhinol. 4 Suppl 2: S18–20. doi:10.1002/alr.21385. PMID 25182349.
  5. 5.0 5.1 5.2 Westman M, Stjärne P, Asarnoj A, Kull I, van Hage M, Wickman M; et al. (2012). "Natural course and comorbidities of allergic and nonallergic rhinitis in children". J Allergy Clin Immunol. 129 (2): 403–8. doi:10.1016/j.jaci.2011.09.036. PMID 22056609.
  6. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A; et al. (2008). "Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)". Allergy. 63 Suppl 86: 8–160. doi:10.1111/j.1398-9995.2007.01620.x. PMID 18331513.
  7. Dykewicz MS, Hamilos DL (2010). "Rhinitis and sinusitis". J Allergy Clin Immunol. 125 (2 Suppl 2): S103–15. doi:10.1016/j.jaci.2009.12.989. PMID 20176255.

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