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{{CMG}}
{{CMG}}


{{SK}}''''' histiocytic lymphoma, histiocytic lymphosarcoma
{{SK}}Histiocytic lymphoma, histiocytic lymphosarcoma


==Overview==
== [[Reticulum cell sarcoma overview|Overview]] ==
A malignant tumor of reticular tissue in the bone that is composed primarily of neoplastic [[histocytes]].


==Pathophysiology==
== [[Reticulum cell sarcoma historical perspective|Historical Perspective]]==
The dominant cell type is thought to be derived from [[histiocytes]] or [[macrophages]].  More recent thinking indicates that this cancer may arise from [[lymphocytes]] or [[immunoblasts]].


==Differentiating Reticulum Cell Sarcoma From Other Diseases==
== [[Reticulum cell sarcoma classification|Classification]] ==
Reticulum cell sarcoma should be distinguished from the following diseases:
*[[Ewing's sarcoma]]
*[[Fibrosarcoma]]
*[[Malignant Fibrous Histiocytoma]]
*[[Metastatic carcinoma]]
*[[Osteomyelitis]]


==Epidemiology and Demographics==
== [[Reticulum cell sarcoma pathophysiology|Pathophysiology]] ==
*Presents in middle age


==Diagnosis==
== [[Reticulum cell sarcoma causes|Causes]] ==
===Symptoms===
*Localized bone pain and tenderness


===Physical Examination===
== [[Reticulum cell sarcoma differential diagnosis|Differentiating Reticulum Cell Sarcoma from other Diseases]] ==
*Tenderness of bone
*Effusion of adjacent joint


===Imaging Findings===
== [[Reticulum cell sarcoma epidemiology and demographics|Epidemiology and Demographics]]==
*Osteolytic lesions with minimal periosteal reactions are present on plain films of the bone


===Pathology===
== [[Reticulum cell sarcoma risk factors|Risk Factors]] ==
*Large, foam filled [[histiocytes]] with numerous [[mitoses]] and scant stroma are present
*Stains for reticulum are positive
*[[Periodic Acid Schiff]] ([[PAS]]) stains are negative


==Treatment==
== [[Reticulum cell sarcoma natural history, complications and prognosis|Natural History, Complications and Prognosis]] ==
===Early stage I tumors===
 
*[[Radiation therapy]] alone
== Diagnosis ==
===Advanced Tumors===
[[Reticulum cell sarcoma history and symptoms|History and Symptoms]] | [[Reticulum cell sarcoma physical examination|Physical Examination]] | [[Reticulum cell sarcoma laboratory findings|Laboratory Findings]] | [[Reticulum cell sarcoma  x ray| X Ray]] | [[Reticulum cell sarcoma CT|CT]] | [[Reticulum cell sarcoma MRI|MRI]] | [[Reticulum cell sarcoma echocardiography or ultrasound| Ultrasound]] | [[Reticulum cell sarcoma other imaging findings|Other Imaging Studies]] | [[Reticulum cell sarcoma other diagnostic studies|Other Diagnostic Studies]]
*[[Radiation therapy]] plus [[chemotherapy]]
 
== Treatment ==
 
[[Reticulum cell sarcoma medical therapy|Medical Therapy]] | [[Reticulum cell sarcoma surgery|Surgery]] | [[Reticulum cell sarcoma primary prevention|Prevention]] | [[Reticulum cell sarcoma future or investigational therapies|Future or Investigational Therapies]] | [[Reticulum cell sarcoma cost-effectiveness of therapy | Cost Effectiveness of Therapy]]
 
==Case Studies==
[[Reticulum cell sarcoma case study one|Case #1]]




==References==
{{Reflist|2}}


[[Category:Hematology]]
[[Category:Hematology]]

Latest revision as of 18:55, 21 September 2012

Reticulum cell sarcoma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Reticulum Cell Sarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

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Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords:Histiocytic lymphoma, histiocytic lymphosarcoma

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Reticulum Cell Sarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI | Ultrasound | Other Imaging Studies | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Prevention | Future or Investigational Therapies | Cost Effectiveness of Therapy

Case Studies

Case #1

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