REXO4: Difference between revisions

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{{Infobox_gene}}
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'''RNA exonuclease 4''' is an [[enzyme]] that in [[Human|humans]] is encoded by the ''REXO4'' [[gene]].<ref name="pmid9325058">{{cite journal | vauthors = Kwiatkowska J, Slomski R, Jozwiak S, Short MP, Kwiatkowski DJ | title = Human XPMC2H: cDNA cloning, mapping to 9q34, genomic structure, and evaluation as TSC1 | journal = Genomics | volume = 44 | issue = 3 | pages = 350–4 |date=Nov 1997 | pmid = 9325058 | pmc =  | doi = 10.1006/geno.1997.4874 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57109| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = REX4, RNA exonuclease 4 homolog (S. cerevisiae)
| HGNCid = 12820
| Symbol = REXO4
| AltSymbols =; XPMC2; XPMC2H
| OMIM = 602930
| ECnumber = 
| Homologene = 1660
| MGIid = 2684957
| GeneAtlas_image1 = PBB_GE_REXO4_218767_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0004527 |text = exonuclease activity}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005730 |text = nucleolus}}
| Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 57109
    | Hs_Ensembl = ENSG00000148300
    | Hs_RefseqProtein = NP_065118
    | Hs_RefseqmRNA = NM_020385
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 135261007
    | Hs_GenLoc_end = 135272985
    | Hs_Uniprot = Q9GZR2
    | Mm_EntrezGene = 227656
    | Mm_Ensembl = ENSMUSG00000052406
    | Mm_RefseqmRNA = NM_207234
    | Mm_RefseqProtein = NP_997117
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 26775572
    | Mm_GenLoc_end = 26786395
    | Mm_Uniprot = Q6PAQ4
  }}
}}
'''REX4, RNA exonuclease 4 homolog (S. cerevisiae)''', also known as '''REXO4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57109| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Kwiatkowska J, Slomski R, Jozwiak S, ''et al.'' |title=Human XPMC2H: cDNA cloning, mapping to 9q34, genomic structure, and evaluation as TSC1. |journal=Genomics |volume=44 |issue= 3 |pages= 350-4 |year= 1997 |pmid= 9325058 |doi= 10.1006/geno.1997.4874 }}
*{{cite journal  | vauthors=Montano MM, Wittmann BM, Bianco NR |title=Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity. |journal=J. Biol. Chem. |volume=275 |issue= 44 |pages= 34306–13 |year= 2000 |pmid= 10908561 |doi= 10.1074/jbc.M003880200 }}
*{{cite journal  | author=Montano MM, Wittmann BM, Bianco NR |title=Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity. |journal=J. Biol. Chem. |volume=275 |issue= 44 |pages= 34306-13 |year= 2000 |pmid= 10908561 |doi= 10.1074/jbc.M003880200 }}
*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal   |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal   |vauthors=Simpson JC, Wellenreuther R, Poustka A, etal |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 | pmc=1083732 }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
*{{cite journal   |vauthors=Scherl A, Couté Y, Déon C, etal |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617 }}
*{{cite journal | author=Scherl A, Couté Y, Déon C, ''et al.'' |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100-9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Humphray SJ, Oliver K, Hunt AR, etal |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 | pmc=2734081 }}
*{{cite journal | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }}
*{{cite journal | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
}}
}}
{{refend}}
{{refend}}


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{{gene-9-stub}}

Latest revision as of 07:38, 10 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

RNA exonuclease 4 is an enzyme that in humans is encoded by the REXO4 gene.[1][2]


References

  1. ↑ Kwiatkowska J, Slomski R, Jozwiak S, Short MP, Kwiatkowski DJ (Nov 1997). "Human XPMC2H: cDNA cloning, mapping to 9q34, genomic structure, and evaluation as TSC1". Genomics. 44 (3): 350–4. doi:10.1006/geno.1997.4874. PMID 9325058.
  2. ↑ "Entrez Gene: REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)".

Further reading



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