Pulmonary edema laboratory tests
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Laboratory findings consistent with the diagnosis of pulmonary edema include hypoxia, hypercapnia, acidosis. Elevated B-type natriuretic peptide (BNP) and cardiac enzyme is usually suggestive of cardiogenic pulmonary edema.
Arterial blood gas test:
- Albumin may be low in pulmonary edema
Liver function tests:
- Elevation in alanine aminotransferase, aspartate aminotransferase and bilirubin may be seen in right ventricular failure as underlying cause of cardiogenic pulmonary edema
Plasma brain natriuretic peptide levels :
- B-type natriuretic peptide (BNP) is elevated in the patient with cardiogenic pulmonary edema.
- A low BNP (<100 pg/ml) makes a cardiac cause very unlikely and is associated with non-cardiogenic pulmonary edema.
Pulmonary capillary wedge pressure(PCWP):
- A wedge pressure of 18 mmHg or higher is usually suggestive of cardiogenic pulmonary edema.
- A wedge pressure of less than 18 mmHg is usually suggestive of non-cardiogenic pulmonary edema.
- Elevated concentration of troponin, may suggestive of damage to myocytes, as underlying cause of cardiogenic pulmonary edema.
Shunt fractions (Qs/Qt):
- Patients with non-cardiogenic pulmonary edema had greater shunt fractions(Qs/Qt) than patients with cardiogenic pulmonary edema.
|Laboratory findings||Cardiac enzymes||BNP||PCWP||QS/QT|
|Cardiogenic pulmonary edema||May be elevated||High||>18 mmHg||Small elevated|
|Noncardiogenic pulmonary edema||Usually normal||Low||<18 mmHg||Large elevated|
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