Pseudoathetosis

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Pseudoathetosis
DiseasesDB 30711

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pseudoathetosis is abnormal writhing movements, usually of the fingers, caused by a failure of joint position sense (proprioception)[1] and indicates disruption of the proprioceptive pathway, from peripheral nerve to parietal cortex.

Presentation

Analogous to Romberg's sign, the abnormal posturing is most pronounced when the eyes are closed as visual inputs are unavailable to guide corrective movements. Paradoxically, eye closure may decrease the amount of movement as the visual cues probably trigger corrective movements which return the limb to the desired "baseline" allowing a new phase of involuntary drift before a subsequent corrective phase occurs.

Differential diagnosis

It may be mistaken for choreoathetosis, however, these abnormal movements are relatively constant irrespective of whether the eyes are open or closed and occur in the absence of proprioceptive loss.

Variants

Hemipseudaoathetosis refers to pseudoathetosis on one side of the body ,usually the upper limb and is most commonly caused by a lesion affecting the cuneate tract or cuneate nucleus in the cervical spine or lower brainstem (medulla) respectively[2][3].

External links

Hemipseudoathetosis video clip

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  1. Spitz M, Costa Machado AA, Carvalho Rdo C; et al. (2006). "Pseudoathetosis: report of three patients". Mov. Disord. 21 (9): 1520–2. doi:10.1002/mds.21014. PMID 16817195.
  2. Gotkine M, Gomori JM (2007). "Hemipseudoathetosis due to a hemorrhage at the cervicomedullary junction". Neurology. 69 (15): 1551. doi:10.1212/01.wnl.0000285506.04246.c2. PMID 17923617.
  3. Ghika J, Bogousslavsky J (1997). "Spinal pseudoathetosis: a rare, forgotten syndrome, with a review of old and recent descriptions". Neurology. 49 (2): 432–7. PMID 9270573.