Protein inhibitor of activated STAT2: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''E3 SUMO-protein ligase PIAS2''' is an [[enzyme]] that in humans is encoded by the ''PIAS2'' [[gene]].<ref name="pmid9724754">{{cite journal | vauthors = Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K | title = Inhibition of Stat1-mediated gene activation by PIAS1 | journal = Proc Natl Acad Sci U S A | volume = 95 | issue = 18 | pages = 10626–31 | date = September 1998 | pmid = 9724754 | pmc = 27945 | doi = 10.1073/pnas.95.18.10626 }}</ref><ref name="pmid9256341">{{cite journal | vauthors = Wu L, Wu H, Ma L, Sangiorgi F, Wu N, Bell JR, Lyons GE, Maxson R | title = Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA | journal = Mech Dev | volume = 65 | issue = 1–2 | pages = 3–17 | date = September 1997 | pmid = 9256341 | pmc =  | doi = 10.1016/S0925-4773(97)00032-4 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PIAS2 protein inhibitor of activated STAT, 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9063| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Protein inhibitor of activated STAT, 2
| HGNCid = 17311
| Symbol = PIAS2
| AltSymbols =; MGC102682; MIZ1; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4; miz
| OMIM = 603567
| ECnumber = 
| Homologene = 20979
| MGIid = 1096566
| GeneAtlas_image1 = PBB_GE_PIAS2_37433_at_tn.png
| GeneAtlas_image2 = PBB_GE_PIAS2_214442_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_PIAS2_214593_at_tn.png
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003702 |text = RNA polymerase II transcription factor activity}} {{GNF_GO|id=GO:0003713 |text = transcription coactivator activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0019789 |text = SUMO ligase activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}} {{GNF_GO|id=GO:0050681 |text = androgen receptor binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006512 |text = ubiquitin cycle}} {{GNF_GO|id=GO:0016925 |text = protein sumoylation}} {{GNF_GO|id=GO:0030521 |text = androgen receptor signaling pathway}} {{GNF_GO|id=GO:0045893 |text = positive regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9063
    | Hs_Ensembl = ENSG00000078043
    | Hs_RefseqProtein = XP_001129747
    | Hs_RefseqmRNA = XM_001129747
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 18
    | Hs_GenLoc_start = 42646058
    | Hs_GenLoc_end = 42751464
    | Hs_Uniprot = O75928
    | Mm_EntrezGene = 17344
    | Mm_Ensembl = ENSMUSG00000025423
    | Mm_RefseqmRNA = XM_990156
    | Mm_RefseqProtein = XP_995250
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 18
    | Mm_GenLoc_start = 77301699
    | Mm_GenLoc_end = 77357244
    | Mm_Uniprot = Q3V3U5
  }}
}}
'''Protein inhibitor of activated STAT, 2''', also known as '''PIAS2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PIAS2 protein inhibitor of activated STAT, 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9063| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Protein inhibitor of activated STAT2 has been shown to [[Protein-protein interaction|interact]] with:
{{PBB_Summary
* [[Androgen receptor]],<ref name = pmid11117529>{{cite journal | vauthors = Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA | title = ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation | journal = Mol. Endocrinol. | volume = 14 | issue = 12 | pages = 1986–2000 | date = December 2000 | pmid = 11117529 | doi = 10.1210/mend.14.12.0569 }}</ref><ref name = pmid9920921>{{cite journal | vauthors = Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Jänne OA, Palvimo JJ | title = A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins | journal = J. Biol. Chem. | volume = 274 | issue = 6 | pages = 3700–4 | date = February 1999 | pmid = 9920921 | doi = 10.1074/jbc.274.6.3700}}</ref>
| section_title =  
* [[DNMT3A]],<ref name = pmid14752048>{{cite journal | vauthors = Ling Y, Sankpal UT, Robertson AK, McNally JG, Karpova T, Robertson KD | title = Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription | journal = Nucleic Acids Res. | volume = 32 | issue = 2 | pages = 598–610 | pmid = 14752048 | pmc = 373322 | doi = 10.1093/nar/gkh195 }}</ref>
| summary_text =  
* [[PARK7]],<ref name = pmid11477070>{{cite journal | vauthors = Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H | title = DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor | journal = J. Biol. Chem. | volume = 276 | issue = 40 | pages = 37556–63 | date = October 2001 | pmid = 11477070 | doi = 10.1074/jbc.M101730200 }}</ref> and
}}
* [[UBE2I]].<ref name = pmid16189514>{{cite journal|authorlink30=Huda Zoghbi| vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}</ref><ref name = pmid14609633>{{cite journal | vauthors = Lee BH, Yoshimatsu K, Maeda A, Ochiai K, Morimatsu M, Araki K, Ogino M, Morikawa S, Arikawa J | title = Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules | journal = Virus Res. | volume = 98 | issue = 1 | pages = 83–91 | date = December 2003 | pmid = 14609633 | doi = 10.1016/j.virusres.2003.09.001}}</ref>


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Cookson MR | title = Pathways to Parkinsonism | journal = Neuron | volume = 37 | issue = 1 | pages = 7–10 | year = 2003 | pmid = 12526767 | doi = 10.1016/S0896-6273(02)01166-2 }}
| citations =
* {{cite journal | vauthors = Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Jänne OA, Palvimo JJ | title = A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins | journal = J. Biol. Chem. | volume = 274 | issue = 6 | pages = 3700–4 | year = 1999 | pmid = 9920921 | doi = 10.1074/jbc.274.6.3700 }}
*{{cite journal | author=Cookson MR |title=Pathways to Parkinsonism. |journal=Neuron |volume=37 |issue= 1 |pages= 7-10 |year= 2003 |pmid= 12526767 |doi= }}
* {{cite journal | vauthors = Minty A, Dumont X, Kaghad M, Caput D | title = Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif | journal = J. Biol. Chem. | volume = 275 | issue = 46 | pages = 36316–23 | year = 2000 | pmid = 10961991 | doi = 10.1074/jbc.M004293200 }}
*{{cite journal  | author=Wu L, Wu H, Ma L, ''et al.'' |title=Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA. |journal=Mech. Dev. |volume=65 |issue= 1-2 |pages= 3-17 |year= 1997 |pmid= 9256341 |doi=  }}
* {{cite journal | vauthors = Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA | title = ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation | journal = Mol. Endocrinol. | volume = 14 | issue = 12 | pages = 1986–2000 | year = 2001 | pmid = 11117529 | doi = 10.1210/mend.14.12.0569 }}
*{{cite journal | author=Liu B, Liao J, Rao X, ''et al.'' |title=Inhibition of Stat1-mediated gene activation by PIAS1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 18 |pages= 10626-31 |year= 1998 |pmid= 9724754 |doi=  }}
* {{cite journal | vauthors = Gross M, Liu B, Tan J, French FS, Carey M, Shuai K | title = Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells | journal = Oncogene | volume = 20 | issue = 29 | pages = 3880–7 | year = 2001 | pmid = 11439351 | doi = 10.1038/sj.onc.1204489 }}
*{{cite journal  | author=Moilanen AM, Karvonen U, Poukka H, ''et al.'' |title=A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins. |journal=J. Biol. Chem. |volume=274 |issue= 6 |pages= 3700-4 |year= 1999 |pmid= 9920921 |doi= }}
* {{cite journal | vauthors = Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H | title = DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor | journal = J. Biol. Chem. | volume = 276 | issue = 40 | pages = 37556–63 | year = 2001 | pmid = 11477070 | doi = 10.1074/jbc.M101730200 }}
*{{cite journal | author=Minty A, Dumont X, Kaghad M, Caput D |title=Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36316-23 |year= 2000 |pmid= 10961991 |doi= 10.1074/jbc.M004293200 }}
* {{cite journal | vauthors = Schmidt D, Müller S | title = Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 5 | pages = 2872–7 | year = 2002 | pmid = 11867732 | pmc = 122440 | doi = 10.1073/pnas.052559499 }}
*{{cite journal | author=Kotaja N, Aittomäki S, Silvennoinen O, ''et al.'' |title=ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation. |journal=Mol. Endocrinol. |volume=14 |issue= 12 |pages= 1986-2000 |year= 2001 |pmid= 11117529 |doi= }}
* {{cite journal | vauthors = Tan JA, Hall SH, Hamil KG, Grossman G, Petrusz P, French FS | title = Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators | journal = J. Biol. Chem. | volume = 277 | issue = 19 | pages = 16993–7001 | year = 2002 | pmid = 11877418 | doi = 10.1074/jbc.M109217200 }}
*{{cite journal | author=Gross M, Liu B, Tan J, ''et al.'' |title=Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells. |journal=Oncogene |volume=20 |issue= 29 |pages= 3880-7 |year= 2001 |pmid= 11439351 |doi= 10.1038/sj.onc.1204489 }}
* {{cite journal | vauthors = Nishida T, Yasuda H | title = PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription | journal = J. Biol. Chem. | volume = 277 | issue = 44 | pages = 41311–7 | year = 2003 | pmid = 12177000 | doi = 10.1074/jbc.M206741200 }}
*{{cite journal | author=Takahashi K, Taira T, Niki T, ''et al.'' |title=DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. |journal=J. Biol. Chem. |volume=276 |issue= 40 |pages= 37556-63 |year= 2001 |pmid= 11477070 |doi= 10.1074/jbc.M101730200 }}
* {{cite journal | vauthors = Tussie-Luna MI, Michel B, Hakre S, Roy AL | title = The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I | journal = J. Biol. Chem. | volume = 277 | issue = 45 | pages = 43185–93 | year = 2003 | pmid = 12193603 | doi = 10.1074/jbc.M207635200 }}
*{{cite journal | author=Schmidt D, Müller S |title=Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 5 |pages= 2872-7 |year= 2002 |pmid= 11867732 |doi= 10.1073/pnas.052559499 }}
* {{cite journal | vauthors = Tussié-Luna MI, Bayarsaihan D, Seto E, Ruddle FH, Roy AL | title = Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 20 | pages = 12807–12 | year = 2002 | pmid = 12239342 | pmc = 130541 | doi = 10.1073/pnas.192464499 }}
*{{cite journal | author=Tan JA, Hall SH, Hamil KG, ''et al.'' |title=Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators. |journal=J. Biol. Chem. |volume=277 |issue= 19 |pages= 16993-7001 |year= 2002 |pmid= 11877418 |doi= 10.1074/jbc.M109217200 }}
* {{cite journal | vauthors = Miyauchi Y, Yogosawa S, Honda R, Nishida T, Yasuda H | title = Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes | journal = J. Biol. Chem. | volume = 277 | issue = 51 | pages = 50131–6 | year = 2003 | pmid = 12393906 | doi = 10.1074/jbc.M208319200 }}
*{{cite journal | author=Nishida T, Yasuda H |title=PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription. |journal=J. Biol. Chem. |volume=277 |issue= 44 |pages= 41311-7 |year= 2003 |pmid= 12177000 |doi= 10.1074/jbc.M206741200 }}
* {{cite journal | vauthors = Arora T, Liu B, He H, Kim J, Murphy TL, Murphy KM, Modlin RL, Shuai K | title = PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4 | journal = J. Biol. Chem. | volume = 278 | issue = 24 | pages = 21327–30 | year = 2003 | pmid = 12716907 | doi = 10.1074/jbc.C300119200 }}
*{{cite journal | author=Tussie-Luna MI, Michel B, Hakre S, Roy AL |title=The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 43185-93 |year= 2003 |pmid= 12193603 |doi= 10.1074/jbc.M207635200 }}
* {{cite journal | vauthors = Ohshima T, Shimotohno K | title = Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4 | journal = J. Biol. Chem. | volume = 278 | issue = 51 | pages = 50833–42 | year = 2004 | pmid = 14514699 | doi = 10.1074/jbc.M307533200 }}
*{{cite journal | author=Tussié-Luna MI, Bayarsaihan D, Seto E, ''et al.'' |title=Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 20 |pages= 12807-12 |year= 2002 |pmid= 12239342 |doi= 10.1073/pnas.192464499 }}
* {{cite journal | vauthors = Lee BH, Yoshimatsu K, Maeda A, Ochiai K, Morimatsu M, Araki K, Ogino M, Morikawa S, Arikawa J | title = Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules | journal = Virus Res. | volume = 98 | issue = 1 | pages = 83–91 | year = 2004 | pmid = 14609633 | doi = 10.1016/j.virusres.2003.09.001 }}
*{{cite journal | author=Miyauchi Y, Yogosawa S, Honda R, ''et al.'' |title=Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes. |journal=J. Biol. Chem. |volume=277 |issue= 51 |pages= 50131-6 |year= 2003 |pmid= 12393906 |doi= 10.1074/jbc.M208319200 }}
* {{cite journal | vauthors = Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM | title = Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region | journal = Genomics | volume = 83 | issue = 1 | pages = 153–67 | year = 2004 | pmid = 14667819 | doi = 10.1016/S0888-7543(03)00235-0 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Arora T, Liu B, He H, ''et al.'' |title=PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. |journal=J. Biol. Chem. |volume=278 |issue= 24 |pages= 21327-30 |year= 2003 |pmid= 12716907 |doi= 10.1074/jbc.C300119200 }}
*{{cite journal | author=Ohshima T, Shimotohno K |title=Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 50833-42 |year= 2004 |pmid= 14514699 |doi= 10.1074/jbc.M307533200 }}
*{{cite journal | author=Lee BH, Yoshimatsu K, Maeda A, ''et al.'' |title=Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules. |journal=Virus Res. |volume=98 |issue= 1 |pages= 83-91 |year= 2004 |pmid= 14609633 |doi= }}
*{{cite journal | author=Lehner B, Semple JI, Brown SE, ''et al.'' |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153-67 |year= 2004 |pmid= 14667819 |doi= }}
}}
{{refend}}
{{refend}}
{{JAK-STAT signaling pathway}}


{{gene-18-stub}}
{{gene-18-stub}}

Latest revision as of 17:13, 8 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

E3 SUMO-protein ligase PIAS2 is an enzyme that in humans is encoded by the PIAS2 gene.[1][2][3]

Interactions

Protein inhibitor of activated STAT2 has been shown to interact with:

References

  1. ↑ Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K (September 1998). "Inhibition of Stat1-mediated gene activation by PIAS1". Proc Natl Acad Sci U S A. 95 (18): 10626–31. doi:10.1073/pnas.95.18.10626. PMC 27945. PMID 9724754.
  2. ↑ Wu L, Wu H, Ma L, Sangiorgi F, Wu N, Bell JR, Lyons GE, Maxson R (September 1997). "Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA". Mech Dev. 65 (1–2): 3–17. doi:10.1016/S0925-4773(97)00032-4. PMID 9256341.
  3. ↑ "Entrez Gene: PIAS2 protein inhibitor of activated STAT, 2".
  4. ↑ Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA (December 2000). "ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation". Mol. Endocrinol. 14 (12): 1986–2000. doi:10.1210/mend.14.12.0569. PMID 11117529.
  5. ↑ Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Jänne OA, Palvimo JJ (February 1999). "A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins". J. Biol. Chem. 274 (6): 3700–4. doi:10.1074/jbc.274.6.3700. PMID 9920921.
  6. ↑ Ling Y, Sankpal UT, Robertson AK, McNally JG, Karpova T, Robertson KD. "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription". Nucleic Acids Res. 32 (2): 598–610. doi:10.1093/nar/gkh195. PMC 373322. PMID 14752048.
  7. ↑ Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H (October 2001). "DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor". J. Biol. Chem. 276 (40): 37556–63. doi:10.1074/jbc.M101730200. PMID 11477070.
  8. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  9. ↑ Lee BH, Yoshimatsu K, Maeda A, Ochiai K, Morimatsu M, Araki K, Ogino M, Morikawa S, Arikawa J (December 2003). "Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules". Virus Res. 98 (1): 83–91. doi:10.1016/j.virusres.2003.09.001. PMID 14609633.

Further reading

  • Cookson MR (2003). "Pathways to Parkinsonism". Neuron. 37 (1): 7–10. doi:10.1016/S0896-6273(02)01166-2. PMID 12526767.
  • Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Jänne OA, Palvimo JJ (1999). "A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins". J. Biol. Chem. 274 (6): 3700–4. doi:10.1074/jbc.274.6.3700. PMID 9920921.
  • Minty A, Dumont X, Kaghad M, Caput D (2000). "Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif". J. Biol. Chem. 275 (46): 36316–23. doi:10.1074/jbc.M004293200. PMID 10961991.
  • Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA (2001). "ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation". Mol. Endocrinol. 14 (12): 1986–2000. doi:10.1210/mend.14.12.0569. PMID 11117529.
  • Gross M, Liu B, Tan J, French FS, Carey M, Shuai K (2001). "Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells". Oncogene. 20 (29): 3880–7. doi:10.1038/sj.onc.1204489. PMID 11439351.
  • Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H (2001). "DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor". J. Biol. Chem. 276 (40): 37556–63. doi:10.1074/jbc.M101730200. PMID 11477070.
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