Primary biliary cirrhosis causes: Difference between revisions

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==Causes==
==Causes==
*The cause of Primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing Primary biliary cirrhosis. <ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546  }} </ref> <ref name="pmid26167070">{{cite journal| author=Reshetnyak VI| title=Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis. | journal=World J Gastroenterol | year= 2015 | volume= 21 | issue= 25 | pages= 7683-708 | pmid=26167070 | doi=10.3748/wjg.v21.i25.7683 | pmc=4491957 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26167070 }} </ref>
*The cause of Primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing Primary biliary cirrhosis. <ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546  }} </ref> <ref name="pmid21529926">{{cite journal| author=Selmi C, Bowlus CL, Gershwin ME, Coppel RL| title=Primary biliary cirrhosis. | journal=Lancet | year= 2011 | volume= 377 | issue= 9777 | pages= 1600-9 | pmid=21529926 | doi=10.1016/S0140-6736(10)61965-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21529926  }} </ref> <ref name="pmid25057950">{{cite journal| author=Juran BD, Lazaridis KN| title=Environmental factors in primary biliary cirrhosis. | journal=Semin Liver Dis | year= 2014 | volume= 34 | issue= 3 | pages= 265-72 | pmid=25057950 | doi=10.1055/s-0034-1383726 | pmc=4232304 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25057950 }} </ref>
*Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing Primary biliary cirrhosis. <ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546  }} </ref> <ref name="pmid26167070">{{cite journal| author=Reshetnyak VI| title=Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis. | journal=World J Gastroenterol | year= 2015 | volume= 21 | issue= 25 | pages= 7683-708 | pmid=26167070 | doi=10.3748/wjg.v21.i25.7683 | pmc=4491957 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26167070 }} </ref>
*Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing Primary biliary cirrhosis. <ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546  }} </ref> <ref name="pmid21529926">{{cite journal| author=Selmi C, Bowlus CL, Gershwin ME, Coppel RL| title=Primary biliary cirrhosis. | journal=Lancet | year= 2011 | volume= 377 | issue= 9777 | pages= 1600-9 | pmid=21529926 | doi=10.1016/S0140-6736(10)61965-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21529926  }} </ref> <ref name="pmid25057950">{{cite journal| author=Juran BD, Lazaridis KN| title=Environmental factors in primary biliary cirrhosis. | journal=Semin Liver Dis | year= 2014 | volume= 34 | issue= 3 | pages= 265-72 | pmid=25057950 | doi=10.1055/s-0034-1383726 | pmc=4232304 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25057950 }} </ref>
*To learn more about the risk factors for the development of Primary biliary cirrhosis, click [[Primary biliary cirrhosis risk factors|here]].
*To learn more about the risk factors for the development of Primary biliary cirrhosis, click [[Primary biliary cirrhosis risk factors|here]].



Revision as of 17:37, 6 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The cause of Primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing Primary biliary cirrhosis. Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing Primary biliary cirrhosis. To review risk factors for the development of Primary biliary cirrhosis, click here.

Causes

  • The cause of Primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing Primary biliary cirrhosis. [1] [2] [3]
  • Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing Primary biliary cirrhosis. [1] [2] [3]
  • To learn more about the risk factors for the development of Primary biliary cirrhosis, click here.

References

  1. 1.0 1.1 Carey EJ, Ali AH, Lindor KD (2015). "Primary biliary cirrhosis". Lancet. 386 (10003): 1565–75. doi:10.1016/S0140-6736(15)00154-3. PMID 26364546.
  2. 2.0 2.1 Selmi C, Bowlus CL, Gershwin ME, Coppel RL (2011). "Primary biliary cirrhosis". Lancet. 377 (9777): 1600–9. doi:10.1016/S0140-6736(10)61965-4. PMID 21529926.
  3. 3.0 3.1 Juran BD, Lazaridis KN (2014). "Environmental factors in primary biliary cirrhosis". Semin Liver Dis. 34 (3): 265–72. doi:10.1055/s-0034-1383726. PMC 4232304. PMID 25057950.

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