Primary biliary cirrhosis MRI: Difference between revisions

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==Overview==
==Overview==
Abdominal MRI may be helpful in the diagnosis of Primary biliary cirrhosis. Findings on MRI that increase the suspicion for Primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign.
Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI that increase the suspicion for primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign.


==MRI==
==MRI==
*Abdominal MRI may be helpful in the diagnosis of Primary biliary cirrhosis. Findings on MRI that increase the suspicion for Primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign. Other characteristic features include: <ref name="pmid18215315">{{cite journal| author=Kumagi T, Heathcote EJ| title=Primary biliary cirrhosis. | journal=Orphanet J Rare Dis | year= 2008 | volume= 3 | issue=  | pages= 1 | pmid=18215315 | doi=10.1186/1750-1172-3-1 | pmc=2266722 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18215315  }} </ref> <ref name="pmid25954476">{{cite journal| author=Purohit T, Cappell MS| title=Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy. | journal=World J Hepatol | year= 2015 | volume= 7 | issue= 7 | pages= 926-41 | pmid=25954476 | doi=10.4254/wjh.v7.i7.926 | pmc=4419097 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25954476  }} </ref> <ref name="pmid20955967">{{cite journal| author=Nguyen DL, Juran BD, Lazaridis KN| title=Primary biliary cirrhosis. | journal=Best Pract Res Clin Gastroenterol | year= 2010 | volume= 24 | issue= 5 | pages= 647-54 | pmid=20955967 | doi=10.1016/j.bpg.2010.07.006 | pmc=2958170 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20955967  }} </ref>
*Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI that increase the suspicion for primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign. Other characteristic features include: <ref name="pmid18215315">{{cite journal| author=Kumagi T, Heathcote EJ| title=Primary biliary cirrhosis. | journal=Orphanet J Rare Dis | year= 2008 | volume= 3 | issue=  | pages= 1 | pmid=18215315 | doi=10.1186/1750-1172-3-1 | pmc=2266722 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18215315  }} </ref> <ref name="pmid25954476">{{cite journal| author=Purohit T, Cappell MS| title=Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy. | journal=World J Hepatol | year= 2015 | volume= 7 | issue= 7 | pages= 926-41 | pmid=25954476 | doi=10.4254/wjh.v7.i7.926 | pmc=4419097 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25954476  }} </ref> <ref name="pmid20955967">{{cite journal| author=Nguyen DL, Juran BD, Lazaridis KN| title=Primary biliary cirrhosis. | journal=Best Pract Res Clin Gastroenterol | year= 2010 | volume= 24 | issue= 5 | pages= 647-54 | pmid=20955967 | doi=10.1016/j.bpg.2010.07.006 | pmc=2958170 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20955967  }} </ref>
**Irregularly appearing regenerative nodules on the hepatic surface
**Irregularly appearing regenerative nodules on the hepatic surface
**Hyperintense periportal region
**Hyperintense periportal region
**Segmental hypertrophy of the caudate lobe
**Segmental hypertrophy of the caudate lobe
**Regional lymphadenopathy
**Regional lymphadenopathy
**splenomegaly
**Splenomegaly
 
 
[[Image:Primary-biliary-cirrhosis.jpg|center|350px|Case courtesy of <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/11816">rID: 11816</a>]]


==References==
==References==

Revision as of 20:40, 6 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:


Overview

Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI that increase the suspicion for primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign.

MRI

  • Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI that increase the suspicion for primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign. Other characteristic features include: [1] [2] [3]
    • Irregularly appearing regenerative nodules on the hepatic surface
    • Hyperintense periportal region
    • Segmental hypertrophy of the caudate lobe
    • Regional lymphadenopathy
    • Splenomegaly


Case courtesy of <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/11816">rID: 11816</a>
Case courtesy of <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/11816">rID: 11816</a>

References

  1. Kumagi T, Heathcote EJ (2008). "Primary biliary cirrhosis". Orphanet J Rare Dis. 3: 1. doi:10.1186/1750-1172-3-1. PMC 2266722. PMID 18215315.
  2. Purohit T, Cappell MS (2015). "Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy". World J Hepatol. 7 (7): 926–41. doi:10.4254/wjh.v7.i7.926. PMC 4419097. PMID 25954476.
  3. Nguyen DL, Juran BD, Lazaridis KN (2010). "Primary biliary cirrhosis". Best Pract Res Clin Gastroenterol. 24 (5): 647–54. doi:10.1016/j.bpg.2010.07.006. PMC 2958170. PMID 20955967.


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