Pleomorphic adenoma diagnostic study of choice

Jump to navigation Jump to search

Pleomorphic adenoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pleomorphic adenoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pleomorphic adenoma diagnostic study of choice On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pleomorphic adenoma diagnostic study of choice

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pleomorphic adenoma diagnostic study of choice

CDC on Pleomorphic adenoma diagnostic study of choice

Pleomorphic adenoma diagnostic study of choice in the news

Blogs on Pleomorphic adenoma diagnostic study of choice

Directions to Hospitals Treating Pleomorphic adenoma

Risk calculators and risk factors for Pleomorphic adenoma diagnostic study of choice

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

MRI is the study of choice for pleomorphic adenoma. On T1-weighted images they show homogeneous intensity, on T2 they show marked hyperintensity reflecting myxochondroid stroma and hypointensity corresponds to fibrous capsule of the tumor. On Gd-T1 imaging it shows heterogeneous enhancement.

Diagnostic Study of Choice

Study of choice

  • MRI is the preferred diagnostic study of choice for pleomorphic adenoma.[1]

The comparison of various diagnostic studies for [disease name]

Test Sensitivity Specificity
MRI 43.9% 95%

[Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity

Diagnostic results
MRI
  • MRI is the imaging modality of choice for pleomorphic adenoma.[2][1]
  • On T1-weighted images:
    • Pleomorphic adenoma's show homogeneous intensity. [3]
  • On T2-weighted images:
    • Marked hyperintensity reflects abundant myxochondroid stroma.[4]
    • Hypointensity reflects the fibrous capsule of the tumor.[4]
  • On Gd-T1weighted images:
    • It shows heterogeneous enhancement.[3]
Sequence of Diagnostic Studies

The various investigations must be performed in the following order:

  • CT is usually the first imaging modality of choice for pleomorphic adenoma.[1]
  • It helps in identifying the lesion and also helps the physician in assessing the extension of the tumor.
  • MRI is the usually ordered investigation next after CT, for an even more detailed study.[1]
  • It is a non-ionizing modality with excellent soft tissue distinction.
  • FNA and biopsy is the definitive method of diagnosis for pleomorphic adenoma.

Name of Diagnostic Criteria

There are no established criteria for the diagnosis of pleomorphic adenoma.

References

  1. 1.0 1.1 1.2 1.3 Rai, Shalu; Rohit, Malik; Kaur, Mandeep; Mukul, Prabhat (2013). "Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report". Dental Hypotheses. 4 (1): 33. doi:10.4103/2155-8213.110181. ISSN 2155-8213.
  2. Ikeda K, Katoh T, Ha-Kawa SK, Iwai H, Yamashita T, Tanaka Y (March 1996). "The usefulness of MR in establishing the diagnosis of parotid pleomorphic adenoma". AJNR Am J Neuroradiol. 17 (3): 555–9. PMID 8881252.
  3. 3.0 3.1 Hisatomi, Miki; Asaumi, Jun-ichi; Yanagi, Yoshinobu; Konouchi, Hironobu; Matsuzaki, Hidenobu; Honda, Yasutoshi; Kishi, Kanji (2003). "Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI". Oral Oncology. 39 (6): 574–579. doi:10.1016/S1368-8375(03)00040-X. ISSN 1368-8375.
  4. 4.0 4.1 Kato H, Kawaguchi M, Ando T, Mizuta K, Aoki M, Matsuo M (August 2018). "Pleomorphic adenoma of salivary glands: common and uncommon CT and MR imaging features". Jpn J Radiol. 36 (8): 463–471. doi:10.1007/s11604-018-0747-y. PMID 29845358.

Template:WH Template:WS