Paroxetine

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Synonyms / Brand Names: Paroxetina, Paroxetine Hcl, Paroxetinum, Aropax, Paxil, Paxil CR, Pexeva, Seroxat, Seroxat CR

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

For major depressive disorder Paroxetine tablets should be administered as a single daily dose with or without food, usually in the morning. The recommended initial dose is 20 mg/day. Patients were dosed in a range of 20 to 50 mg/day in the clinical trials demonstrating the effectiveness of Paroxetine hydrochloride in the treatment of major depressive disorder. As with all drugs effective in the treatment of major depressive disorder, the full effect may be delayed. Some patients not responding to a 20 mg dose may benefit from dose increases, in 10 mg/day increments, up to a maximum of 50 mg/day. Dose changes should occur at intervals of at least 1 week.

For obsessive compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder dosing information see Instructions for Administration



FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español






FDA Package Insert Resources

Indications

Contraindications

Side Effects

Drug Interactions

Precautions

Overdose

Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA label

FDA on Paroxetine

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Publication Resources

Most Recent Articles on Paroxetine

Review Articles on Paroxetine

Articles on Paroxetine in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Paroxetine

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Trial Resources

Ongoing Trials with Paroxetine at Clinical Trials.gov

Trial Results with Paroxetine

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Paroxetine

Cochrane Collaboration on Paroxetine

Cost Effectiveness of Paroxetine

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Media Resources

Powerpoint Slides on Paroxetine

Images of Paroxetine

Podcasts & MP3s on Paroxetine

Videos on Paroxetine

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Patient Resources

Patient Information from National Library of Medicine

Patient Resources on Paroxetine

Discussion Groups on Paroxetine

Patient Handouts on Paroxetine

Blogs on Paroxetine

Paroxetine in the News

Paroxetine in the Marketplace

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International Resources

Paroxetine en Español

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Adapted from the FDA Package Insert.