Papillary thyroid cancer echocardiography or ultrasound: Difference between revisions

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__NOTOC__
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{{Papillary thyroid cancer}}
{{Papillary thyroid cancer}}
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}} {{Sahar}} {{Ammu}}
==Overview==
==Overview==
Neck ultrasound may be performed to detect papillar thyroid cancer.
Neck [[ultrasound]] may be performed to detect papillary thyroid cancer. [[Ultrasound imaging]] findings suggestive of [[malignant]] [[thyroid nodule]] include [[microcalcification]], peripheral and coarse [[calcification]], [[solid]], hypoechoic [[nodule]], locally invaded [[nodule]], and presence of posterior acoustic shadowing.
==Key Ultrasound Findings in Papillary thyroid cancer==
==Ultrasound==
The ultrasound is a useful test to distinguish solid from cystic lesions and to identify calcifications.<ref>{{cite news|url=http://findarticles.com/p/articles/mi_qa3725/is_200607/ai_n16598095/|title=Papillary Thyroid Carcinoma: An Overview|date=|accessdate= 2010-07-15 | work=Archives of Pathology & Laboratory Medicine | year=2006}}</ref>
*[[Ultrasound imaging]] is useful in the [[diagnosis]] and management of [[thyroid cancer]]. It is used for:<ref name="CoquiaChu2014">{{cite journal|last1=Coquia|first1=Stephanie F.|last2=Chu|first2=Linda C.|last3=Hamper|first3=Ulrike M.|title=The Role of Sonography in Thyroid Cancer|journal=Radiologic Clinics of North America|volume=52|issue=6|year=2014|pages=1283–1294|issn=00338389|doi=10.1016/j.rcl.2014.07.007}}</ref><ref name="Stulak2006">{{cite journal|last1=Stulak|first1=John M.|title=Value of Preoperative Ultrasonography in the Surgical Management of Initial and Reoperative Papillary Thyroid Cancer|journal=Archives of Surgery|volume=141|issue=5|year=2006|pages=489|issn=0004-0010|doi=10.1001/archsurg.141.5.489}}</ref>
* The thyroid ultrasound is also very effective to discover microcarcinomas, which refer to very small carcinomas (<1&nbsp;cm).Papillary carcinoma within the thyroid usually appears as a solitary mass usually with an irregular outline, located in the subcapsular region and demonstrating vascularity.<ref name="pmid15770036">{{cite journal| author=Lyshchik A, Drozd V, Demidchik Y, Reiners C| title=Diagnosis of thyroid cancer in children: value of gray-scale and power doppler US. | journal=Radiology | year= 2005 | volume= 235 | issue= 2 | pages= 604-13 | pmid=15770036 | doi=10.1148/radiol.2352031942 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15770036  }} </ref> Small punctate regions of echogenicity representing microcalcifications (psammoma bodies) may be present.<ref name="pmid17579175">{{cite journal| author=Kwak JY, Kim EK, Son EJ, Kim MJ, Oh KK, Kim JY et al.| title=Papillary thyroid carcinoma manifested solely as microcalcifications on sonography. | journal=AJR Am J Roentgenol | year= 2007 | volume= 189 | issue= 1 | pages= 227-31 | pmid=17579175 | doi=10.2214/AJR.06.0750 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17579175  }} </ref>
**Evaluation of [[thyroid nodule]] characteristics
* Lymph node metastases have a tendency to completely cavitate (40%), and although usually multiple, in a minority of cases (6%) a single completely cystic node may be present. They tend to have septations, mural nodules and relatively thick walls.<ref name="pmid11856700">{{cite journal| author=Wunderbaldinger P, Harisinghani MG, Hahn PF, Daniels GH, Turetschek K, Simeone J et al.| title=Cystic lymph node metastases in papillary thyroid carcinoma. | journal=AJR Am J Roentgenol | year= 2002 | volume= 178 | issue= 3 | pages= 693-7 | pmid=11856700 | doi=10.2214/ajr.178.3.1780693 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11856700  }} </ref>
**Determination of [[nodule]] location during [[fine needle aspiration]] study
* Very few radiologists would aspirate a lesion under 10 mm in diameter for 3 reasons: small solid  lesions under 10 mm are very common in the general population (and often often multiple. Depending on which reference you use, up to 50% of the general population will have thyroid nodules of some description on high resolution thyroid ultrasound<ref name="pmid22313412">{{cite journal| author=Chung AY, Tran TB, Brumund KT, Weisman RA, Bouvet M| title=Metastases to the thyroid: a review of the literature from the last decade. | journal=Thyroid | year= 2012 | volume= 22 | issue= 3 | pages= 258-68 | pmid=22313412 | doi=10.1089/thy.2010.0154 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22313412  }} </ref>) , the possibility of sampling error and patient distress.
**Assessment of adjacent lymph node for the purpose of staging the cancer
* A lesion that enlarges with follow up is a relatively strong indication for FNA of the lesion. In patients with pathological cervical nodes on ultrasound, any thyroid lesion should likely be aspirated.
**Post-surgical surveillance for early detection of tumor recurrence and/or nodal [[metastatic]] [[disease]]
* In every day ultrasound practice, PTC most commonly has poorly defined margins and/or calcifications (which may be macrocalcifications). There is a poor correlation between blood flow and malignancy in practice. Aspiration of simple cysts of the thyroid lesions does not yield malignant cells and cysts can safely be followed up in the context of excluding malignancy.
*In summary, [[ultrasound imaging]] findings suggestive of [[malignant]] [[thyroid nodule]] include:
**Microcalcification
**Peripheral, coarse [[calcification]]
**Solid, hypoechoic [[nodule]]
**Locally invaded [[nodule]] (more commonly seen in [[anaplastic thyroid cancer]] and primary [[thyroid]] [[lymphoma]])
**High anteroposterior/width ratio
**Irregular nodular margin
**Adjacent suspicious [[lymph node]] with a size greater than 2 cm
**Presence of posterior acoustic shadowing
*Additionally, [[ultrasound imaging]] has been observed to be useful in the [[diagnosis]] of non-palpable [[lymph node]] [[metastasis]] when used preoperatively.
*Key [[ultrasound]] findings in papillary thyroid cancer include:
**Hypoechoic [[nodule]] in the majority of cases
**Microclacifications that are seen as tiny punctate echogenic foci within the [[nodule]] (most common finding)
**Posterior acoustic shadowing from the edges of the [[nodule]]


==Ultrasound Examples of Papillary thyroid cancer==
'''Ultrasound examples of papillary thyroid cancer'''
[[File:Papillary thyroid cancer ultrasound 06.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound 06.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound 2.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound 2.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound.jpg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound.jpg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]


[[File:Papillary thyroid cancer Ultrasound 04.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer Ultrasound 04.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]


[[File:Papillary thyroid cancer ultrasound 3.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound 3.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]


[[File:Papillary thyroid cancer ultrasound 05.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name=radio> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]
[[File:Papillary thyroid cancer ultrasound 05.jpeg|thumb|center|Papillary thyroid cancer ultrasound<ref name="radio"> Image courtesy of  Dr Garth Kruger. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/articles/papillary-thyroid-cancer ‘’here’’].[http://radiopaedia.org/licence Creative Commons BY-SA-NC]</ref>]]


==References==
==References==
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Latest revision as of 23:34, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Ammu Susheela, M.D. [3]

Overview

Neck ultrasound may be performed to detect papillary thyroid cancer. Ultrasound imaging findings suggestive of malignant thyroid nodule include microcalcification, peripheral and coarse calcification, solid, hypoechoic nodule, locally invaded nodule, and presence of posterior acoustic shadowing.

Ultrasound

Ultrasound examples of papillary thyroid cancer

Papillary thyroid cancer ultrasound[3]
Papillary thyroid cancer ultrasound[3]
Papillary thyroid cancer ultrasound[3]
Papillary thyroid cancer ultrasound[3]
Papillary thyroid cancer ultrasound[3]
Papillary thyroid cancer ultrasound[3]

References

  1. Coquia, Stephanie F.; Chu, Linda C.; Hamper, Ulrike M. (2014). "The Role of Sonography in Thyroid Cancer". Radiologic Clinics of North America. 52 (6): 1283–1294. doi:10.1016/j.rcl.2014.07.007. ISSN 0033-8389.
  2. Stulak, John M. (2006). "Value of Preoperative Ultrasonography in the Surgical Management of Initial and Reoperative Papillary Thyroid Cancer". Archives of Surgery. 141 (5): 489. doi:10.1001/archsurg.141.5.489. ISSN 0004-0010.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Image courtesy of Dr Garth Kruger. Radiopaedia (original file ‘’here’’.Creative Commons BY-SA-NC

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