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{{Infobox_gene}}
{{PBB_Controls
'''Plexin B1''' is a [[protein]] of the [[plexin]] family that in humans is encoded by the ''PLXNB1'' [[gene]].<ref name="pmid8570614">{{cite journal | vauthors = Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM | title = A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 2 | pages = 674–8 | date = Mar 1996 | pmid = 8570614 | pmc = 40111 | doi = 10.1073/pnas.93.2.674 }}</ref><ref name="pmid11035813">{{cite journal | vauthors = Vikis HG, Li W, He Z, Guan KL | title = The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner | journal = Proc Natl Acad Sci U S A | volume = 97 | issue = 23 | pages = 12457–62 | date = Nov 2000 | pmid = 11035813 | pmc = 18785 | doi = 10.1073/pnas.220421797 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PLXNB1 plexin B1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5364| accessdate = }}</ref>
| update_page = yes
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| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Plexin B1
| HGNCid = 9103
| Symbol = PLXNB1
| AltSymbols =; KIAA0407; PLEXIN-B1; PLXN5; SEP
| OMIM = 601053
| ECnumber = 
| Homologene = 20588
| MGIid = 2154238
| GeneAtlas_image1 = PBB_GE_PLXNB1_215807_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_PLXNB1_215668_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0017154 |text = semaphorin receptor activity}} {{GNF_GO|id=GO:0030215 |text = semaphorin receptor binding}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007242 |text = intracellular signaling cascade}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0016477 |text = cell migration}} {{GNF_GO|id=GO:0050772 |text = positive regulation of axonogenesis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5364
    | Hs_Ensembl = ENSG00000164050
    | Hs_RefseqProtein = NP_002664
    | Hs_RefseqmRNA = NM_002673
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 48420266
    | Hs_GenLoc_end = 48446464
    | Hs_Uniprot = O43157
    | Mm_EntrezGene = 235611
    | Mm_Ensembl = ENSMUSG00000053646
    | Mm_RefseqmRNA = NM_172775
    | Mm_RefseqProtein = NP_766363
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 9
    | Mm_GenLoc_start = 108952998
    | Mm_GenLoc_end = 108977323
    | Mm_Uniprot = Q8CJH3
  }}
}}
'''Plexin B1''', also known as '''PLXNB1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PLXNB1 plexin B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5364| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Within neural tissues, the [[plexin]] family serves as transmembrane receptors for [[Semaphorins]].<ref>{{cite journal | vauthors = Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG | title = B plexins activate Rho through PDZ-RhoGEF. | journal = FEBS Letters | volume = 529 | issue = 2-3 | pages = 168–72 | date = Oct 9, 2002 | pmid = 12372594 | doi = 10.1016/s0014-5793(02)03323-9 }}</ref> Outside of neural tissues, Plexin B1 is implicated in the control of cell migration.<ref>{{cite journal | vauthors = Basile JR, Afkhami T, Gutkind JS | title = Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway. | journal = Molecular and Cellular Biology | volume = 25 | issue = 16 | pages = 6889–98 | date = Aug 2005 | pmid = 16055703 | pmc = 1190270 | doi = 10.1128/mcb.25.16.6889-6898.2005 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
PLXNB1 has been shown to [[Protein-protein interaction|interact]] with [[ARHGEF12]],<ref name=pmid12220504>{{cite journal | vauthors = Hirotani M, Ohoka Y, Yamamoto T, Nirasawa H, Furuyama T, Kogo M, Matsuya T, Inagaki S | title = Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors | journal = Biochem. Biophys. Res. Commun. | volume = 297 | issue = 1 | pages = 32–7 | date = Sep 2002 | pmid = 12220504 | doi = 10.1016/S0006-291X(02)02122-8 }}</ref> [[Rnd1]]<ref name=pmid12730235>{{cite journal | vauthors = Oinuma I, Katoh H, Harada A, Negishi M | title = Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells | journal = J. Biol. Chem. | volume = 278 | issue = 28 | pages = 25671–7 | date = Jul 2003 | pmid = 12730235 | doi = 10.1074/jbc.M303047200 }}</ref> and [[ARHGEF11]].<ref name=pmid12220504/><ref name=pmid12730235/><ref name=pmid12183458>{{cite journal | vauthors = Perrot V, Vazquez-Prado J, Gutkind JS | title = Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF | journal = J. Biol. Chem. | volume = 277 | issue = 45 | pages = 43115–20 | date = Nov 2002 | pmid = 12183458 | doi = 10.1074/jbc.M206005200 }}</ref><ref name=pmid12123608>{{cite journal | vauthors = Swiercz JM, Kuner R, Behrens J, Offermanns S | title = Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology | journal = Neuron | volume = 35 | issue = 1 | pages = 51–63 | date = Jul 2002 | pmid = 12123608 | doi = 10.1016/S0896-6273(02)00750-X }}</ref>
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res. | volume = 4 | issue = 5 | pages = 307–13 | year = 1998 | pmid = 9455477 | doi = 10.1093/dnares/4.5.307 }}
| citations =
* {{cite journal | vauthors = Tamagnone L, Artigiani S, Chen H, He Z, Ming GI, Song H, Chedotal A, Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM | title = Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates | journal = Cell | volume = 99 | issue = 1 | pages = 71–80 | year = 1999 | pmid = 10520995 | doi = 10.1016/S0092-8674(00)80063-X }}
*{{cite journal | author=Maestrini E, Tamagnone L, Longati P, ''et al.'' |title=A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 2 |pages= 674-8 |year= 1996 |pmid= 8570614 |doi=  }}
* {{cite journal | vauthors = Vikis HG, Li W, Guan KL | title = The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding | journal = Genes Dev. | volume = 16 | issue = 7 | pages = 836–45 | year = 2002 | pmid = 11937491 | pmc = 186329 | doi = 10.1101/gad.966402 }}
*{{cite journal  | author=Ishikawa K, Nagase T, Nakajima D, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=4 |issue= 5 |pages= 307-13 |year= 1998 |pmid= 9455477 |doi= }}
* {{cite journal | vauthors = Swiercz JM, Kuner R, Behrens J, Offermanns S | title = Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology | journal = Neuron | volume = 35 | issue = 1 | pages = 51–63 | year = 2002 | pmid = 12123608 | doi = 10.1016/S0896-6273(02)00750-X }}
*{{cite journal | author=Tamagnone L, Artigiani S, Chen H, ''et al.'' |title=Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. |journal=Cell |volume=99 |issue= 1 |pages= 71-80 |year= 1999 |pmid= 10520995 |doi=  }}
* {{cite journal | vauthors = Perrot V, Vazquez-Prado J, Gutkind JS | title = Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF | journal = J. Biol. Chem. | volume = 277 | issue = 45 | pages = 43115–20 | year = 2003 | pmid = 12183458 | doi = 10.1074/jbc.M206005200 }}
*{{cite journal  | author=Vikis HG, Li W, He Z, Guan KL |title=The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 23 |pages= 12457-62 |year= 2001 |pmid= 11035813 |doi= 10.1073/pnas.220421797 }}
* {{cite journal | vauthors = Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL | title = The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 19 | pages = 12085–90 | year = 2002 | pmid = 12196628 | pmc = 129402 | doi = 10.1073/pnas.142433199 }}
*{{cite journal | author=Vikis HG, Li W, Guan KL |title=The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding. |journal=Genes Dev. |volume=16 |issue= 7 |pages= 836-45 |year= 2002 |pmid= 11937491 |doi= 10.1101/gad.966402 }}
* {{cite journal | vauthors = Giordano S, Corso S, Conrotto P, Artigiani S, Gilestro G, Barberis D, Tamagnone L, Comoglio PM | title = The semaphorin 4D receptor controls invasive growth by coupling with Met | journal = Nat. Cell Biol. | volume = 4 | issue = 9 | pages = 720–4 | year = 2002 | pmid = 12198496 | doi = 10.1038/ncb843 }}
*{{cite journal | author=Swiercz JM, Kuner R, Behrens J, Offermanns S |title=Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. |journal=Neuron |volume=35 |issue= 1 |pages= 51-63 |year= 2002 |pmid= 12123608 |doi= }}
* {{cite journal | vauthors = Hirotani M, Ohoka Y, Yamamoto T, Nirasawa H, Furuyama T, Kogo M, Matsuya T, Inagaki S | title = Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors | journal = Biochem. Biophys. Res. Commun. | volume = 297 | issue = 1 | pages = 32–7 | year = 2002 | pmid = 12220504 | doi = 10.1016/S0006-291X(02)02122-8 }}
*{{cite journal | author=Perrot V, Vazquez-Prado J, Gutkind JS |title=Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 43115-20 |year= 2003 |pmid= 12183458 |doi= 10.1074/jbc.M206005200 }}
* {{cite journal | vauthors = Granziero L, Circosta P, Scielzo C, Frisaldi E, Stella S, Geuna M, Giordano S, Ghia P, Caligaris-Cappio F | title = CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes | journal = Blood | volume = 101 | issue = 5 | pages = 1962–9 | year = 2003 | pmid = 12406905 | doi = 10.1182/blood-2002-05-1339 }}
*{{cite journal | author=Aurandt J, Vikis HG, Gutkind JS, ''et al.'' |title=The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 19 |pages= 12085-90 |year= 2002 |pmid= 12196628 |doi= 10.1073/pnas.142433199 }}
* {{cite journal | vauthors = Artigiani S, Barberis D, Fazzari P, Longati P, Angelini P, van de Loo JW, Comoglio PM, Tamagnone L | title = Functional regulation of semaphorin receptors by proprotein convertases | journal = J. Biol. Chem. | volume = 278 | issue = 12 | pages = 10094–101 | year = 2003 | pmid = 12533544 | doi = 10.1074/jbc.M210156200 }}
*{{cite journal | author=Giordano S, Corso S, Conrotto P, ''et al.'' |title=The semaphorin 4D receptor controls invasive growth by coupling with Met. |journal=Nat. Cell Biol. |volume=4 |issue= 9 |pages= 720-4 |year= 2002 |pmid= 12198496 |doi= 10.1038/ncb843 }}
* {{cite journal | vauthors = Usui H, Taniguchi M, Yokomizo T, Shimizu T | title = Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains | journal = Biochem. Biophys. Res. Commun. | volume = 300 | issue = 4 | pages = 927–31 | year = 2003 | pmid = 12559962 | doi = 10.1016/S0006-291X(02)02966-2 }}
*{{cite journal | author=Hirotani M, Ohoka Y, Yamamoto T, ''et al.'' |title=Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors. |journal=Biochem. Biophys. Res. Commun. |volume=297 |issue= 1 |pages= 32-7 |year= 2002 |pmid= 12220504 |doi= }}
* {{cite journal | vauthors = Oinuma I, Katoh H, Harada A, Negishi M | title = Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells | journal = J. Biol. Chem. | volume = 278 | issue = 28 | pages = 25671–7 | year = 2003 | pmid = 12730235 | doi = 10.1074/jbc.M303047200 }}
*{{cite journal | author=Granziero L, Circosta P, Scielzo C, ''et al.'' |title=CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes. |journal=Blood |volume=101 |issue= 5 |pages= 1962-9 |year= 2003 |pmid= 12406905 |doi= 10.1182/blood-2002-05-1339 }}
* {{cite journal | vauthors = Conrotto P, Corso S, Gamberini S, Comoglio PM, Giordano S | title = Interplay between scatter factor receptors and B plexins controls invasive growth | journal = Oncogene | volume = 23 | issue = 30 | pages = 5131–7 | year = 2004 | pmid = 15184888 | doi = 10.1038/sj.onc.1207650 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Swiercz JM, Kuner R, Offermanns S | title = Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2 | journal = J. Cell Biol. | volume = 165 | issue = 6 | pages = 869–80 | year = 2004 | pmid = 15210733 | pmc = 2172401 | doi = 10.1083/jcb.200312094 }}
*{{cite journal  | author=Artigiani S, Barberis D, Fazzari P, ''et al.'' |title=Functional regulation of semaphorin receptors by proprotein convertases. |journal=J. Biol. Chem. |volume=278 |issue= 12 |pages= 10094-101 |year= 2003 |pmid= 12533544 |doi= 10.1074/jbc.M210156200 }}
* {{cite journal | vauthors = Oinuma I, Ishikawa Y, Katoh H, Negishi M | title = The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras | journal = Science | volume = 305 | issue = 5685 | pages = 862–5 | year = 2004 | pmid = 15297673 | doi = 10.1126/science.1097545 }}
*{{cite journal | author=Usui H, Taniguchi M, Yokomizo T, Shimizu T |title=Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains. |journal=Biochem. Biophys. Res. Commun. |volume=300 |issue= 4 |pages= 927-31 |year= 2003 |pmid= 12559962 |doi= }}
* {{cite journal | vauthors = Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio PM, Bussolino F, Giordano S | title = Sema4D induces angiogenesis through Met recruitment by Plexin B1 | journal = Blood | volume = 105 | issue = 11 | pages = 4321–9 | year = 2005 | pmid = 15632204 | doi = 10.1182/blood-2004-07-2885 }}
*{{cite journal | author=Oinuma I, Katoh H, Harada A, Negishi M |title=Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells. |journal=J. Biol. Chem. |volume=278 |issue= 28 |pages= 25671-7 |year= 2003 |pmid= 12730235 |doi= 10.1074/jbc.M303047200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Conrotto P, Corso S, Gamberini S, ''et al.'' |title=Interplay between scatter factor receptors and B plexins controls invasive growth. |journal=Oncogene |volume=23 |issue= 30 |pages= 5131-7 |year= 2004 |pmid= 15184888 |doi= 10.1038/sj.onc.1207650 }}
*{{cite journal | author=Swiercz JM, Kuner R, Offermanns S |title=Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2. |journal=J. Cell Biol. |volume=165 |issue= 6 |pages= 869-80 |year= 2004 |pmid= 15210733 |doi= 10.1083/jcb.200312094 }}
*{{cite journal | author=Oinuma I, Ishikawa Y, Katoh H, Negishi M |title=The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras. |journal=Science |volume=305 |issue= 5685 |pages= 862-5 |year= 2004 |pmid= 15297673 |doi= 10.1126/science.1097545 }}
*{{cite journal | author=Conrotto P, Valdembri D, Corso S, ''et al.'' |title=Sema4D induces angiogenesis through Met recruitment by Plexin B1. |journal=Blood |volume=105 |issue= 11 |pages= 4321-9 |year= 2005 |pmid= 15632204 |doi= 10.1182/blood-2004-07-2885 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 18:20, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene.[1][2][3]

Function

Within neural tissues, the plexin family serves as transmembrane receptors for Semaphorins.[4] Outside of neural tissues, Plexin B1 is implicated in the control of cell migration.[5]

Interactions

PLXNB1 has been shown to interact with ARHGEF12,[6] Rnd1[7] and ARHGEF11.[6][7][8][9]

References

  1. ↑ Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM (Mar 1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc Natl Acad Sci U S A. 93 (2): 674–8. doi:10.1073/pnas.93.2.674. PMC 40111. PMID 8570614.
  2. ↑ Vikis HG, Li W, He Z, Guan KL (Nov 2000). "The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner". Proc Natl Acad Sci U S A. 97 (23): 12457–62. doi:10.1073/pnas.220421797. PMC 18785. PMID 11035813.
  3. ↑ "Entrez Gene: PLXNB1 plexin B1".
  4. ↑ Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (Oct 9, 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. 529 (2–3): 168–72. doi:10.1016/s0014-5793(02)03323-9. PMID 12372594.
  5. ↑ Basile JR, Afkhami T, Gutkind JS (Aug 2005). "Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway". Molecular and Cellular Biology. 25 (16): 6889–98. doi:10.1128/mcb.25.16.6889-6898.2005. PMC 1190270. PMID 16055703.
  6. ↑ 6.0 6.1 Hirotani M, Ohoka Y, Yamamoto T, Nirasawa H, Furuyama T, Kogo M, Matsuya T, Inagaki S (Sep 2002). "Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors". Biochem. Biophys. Res. Commun. 297 (1): 32–7. doi:10.1016/S0006-291X(02)02122-8. PMID 12220504.
  7. ↑ 7.0 7.1 Oinuma I, Katoh H, Harada A, Negishi M (Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells". J. Biol. Chem. 278 (28): 25671–7. doi:10.1074/jbc.M303047200. PMID 12730235.
  8. ↑ Perrot V, Vazquez-Prado J, Gutkind JS (Nov 2002). "Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF". J. Biol. Chem. 277 (45): 43115–20. doi:10.1074/jbc.M206005200. PMID 12183458.
  9. ↑ Swiercz JM, Kuner R, Behrens J, Offermanns S (Jul 2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology". Neuron. 35 (1): 51–63. doi:10.1016/S0896-6273(02)00750-X. PMID 12123608.

Further reading


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