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{{Infobox_gene}}
{{PBB_Controls
'''Peroxisomal biogenesis factor 19''' is a [[protein]] that in humans is encoded by the ''PEX19'' [[gene]].<ref name="pmid9339377">{{cite journal | vauthors = Kammerer S, Arnold N, Gutensohn W, Mewes HW, Kunau WH, Höfler G, Roscher AA, Braun A | title = Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein | journal = Genomics | volume = 45 | issue = 1 | pages = 200–10 | date = November 1997 | pmid = 9339377 | pmc =  | doi = 10.1006/geno.1997.4914 }}</ref><ref name="pmid10051604">{{cite journal | vauthors = Matsuzono Y, Kinoshita N, Tamura S, Shimozawa N, Hamasaki M, Ghaedi K, Wanders RJ, Suzuki Y, Kondo N, Fujiki Y | title = Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly | journal = Proc Natl Acad Sci U S A | volume = 96 | issue = 5 | pages = 2116–21 | date = April 1999 | pmid = 10051604 | pmc = 26746 | doi = 10.1073/pnas.96.5.2116 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PEX19 peroxisomal biogenesis factor 19| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5824| accessdate = }}</ref>
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| update_protein_box = yes
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| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Peroxisomal biogenesis factor 19
| HGNCid = 9713
| Symbol = PEX19
| AltSymbols =; D1S2223E; HK33; PMP1; PMPI; PXF; PXMP1
| OMIM = 600279
| ECnumber = 
| Homologene = 37696
| MGIid = 1334458
| GeneAtlas_image1 = PBB_GE_PEX19_201707_at_tn.png
| GeneAtlas_image2 = PBB_GE_PEX19_201706_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005777 |text = peroxisome}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006625 |text = protein targeting to peroxisome}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5824
    | Hs_Ensembl = ENSG00000162735
    | Hs_RefseqProtein = NP_002848
    | Hs_RefseqmRNA = NM_002857
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 158513223
    | Hs_GenLoc_end = 158521560
    | Hs_Uniprot = P40855
    | Mm_EntrezGene = 19298
    | Mm_Ensembl = ENSMUSG00000003464
    | Mm_RefseqmRNA = NM_023041
    | Mm_RefseqProtein = NP_075528
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 173963447
    | Mm_GenLoc_end = 173972455
    | Mm_Uniprot = Q3TDI5
  }}
}}
'''Peroxisomal biogenesis factor 19''', also known as '''PEX19''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PEX19 peroxisomal biogenesis factor 19| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5824| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
PEX19 has been shown to [[Protein-protein interaction|interact]] with:
{{PBB_Summary
{{div col|colwidth=20em}}
| section_title =  
* [[ABCD1]],<ref name = pmid11883941/><ref name = pmid10777694/>
| summary_text =  
* [[ABCD2]],<ref name = pmid11883941/><ref name = pmid10777694/>
}}
* [[ABCD3]],<ref name = pmid11883941>{{cite journal | vauthors = Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC | title = Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly | journal = Biochem. Biophys. Res. Commun. | volume = 291 | issue = 5 | pages = 1180–6 | date = March 2002 | pmid = 11883941 | doi = 10.1006/bbrc.2002.6568 }}</ref><ref name = pmid10777694>{{cite journal | vauthors = Gloeckner CJ, Mayerhofer PU, Landgraf P, Muntau AC, Holzinger A, Gerber JK, Kammerer S, Adamski J, Roscher AA | title = Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p | journal = Biochem. Biophys. Res. Commun. | volume = 271 | issue = 1 | pages = 144–50 | date = April 2000 | pmid = 10777694 | doi = 10.1006/bbrc.2000.2572 }}</ref><ref name = pmid10704444/><ref name = pmid11453642>{{cite journal | vauthors = Biermanns M, Gärtner J | title = Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes | journal = Biochem. Biophys. Res. Commun. | volume = 285 | issue = 3 | pages = 649–55 | date = July 2001 | pmid = 11453642 | doi = 10.1006/bbrc.2001.5220 }}</ref>
* [[PEX10]],<ref name = pmid10704444>{{cite journal | vauthors = Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ | title = PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis | journal = J. Cell Biol. | volume = 148 | issue = 5 | pages = 931–44 | date = March 2000 | pmid = 10704444 | pmc = 2174547 | doi = 10.1083/jcb.148.5.931}}</ref><ref name = pmid11390669>{{cite journal | vauthors = Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP | title = Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences | journal = Mol. Cell. Biol. | volume = 21 | issue = 13 | pages = 4413–24 | date = July 2001 | pmid = 11390669 | pmc = 87101 | doi = 10.1128/MCB.21.13.4413-4424.2001 }}</ref>
* [[PEX11B]],<ref name = pmid10704444/><ref name = pmid11390669/>
* [[PEX12]],<ref name = pmid10704444/><ref name = pmid11390669/>
* [[PEX13]],<ref name = pmid10704444/><ref name = pmid11390669/>
* [[PEX16]],<ref name = pmid11390669/> and
* [[PEX3]].<ref name = pmid11883941/><ref name = pmid10704444/><ref name = pmid11390669/><ref name = pmid16189514>{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}</ref>
{{Div col end}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Braun A, Kammerer S, Weissenhorn W, Weiss EH, Cleve H | title = Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1 | journal = Gene | volume = 146 | issue = 2 | pages = 291–5 | year = 1994 | pmid = 8076834 | doi = 10.1016/0378-1119(94)90308-5 }}
| citations =
* {{cite journal | vauthors = Götte K, Girzalsky W, Linkert M, Baumgart E, Kammerer S, Kunau WH, Erdmann R | title = Pex19p, a Farnesylated Protein Essential for Peroxisome Biogenesis | journal = Mol. Cell. Biol. | volume = 18 | issue = 1 | pages = 616–28 | year = 1998 | pmid = 9418908 | pmc = 121529 | doi =  }}
*{{cite journal | author=Braun A, Kammerer S, Weissenhorn W, ''et al.'' |title=Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1. |journal=Gene |volume=146 |issue= 2 |pages= 291-5 |year= 1994 |pmid= 8076834 |doi=  }}
* {{cite journal | vauthors = Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ | title = Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis | journal = J. Cell Biol. | volume = 148 | issue = 5 | pages = 931–44 | year = 2000 | pmid = 10704444 | pmc = 2174547 | doi = 10.1083/jcb.148.5.931 }}
*{{cite journal  | author=Kammerer S, Arnold N, Gutensohn W, ''et al.'' |title=Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein. |journal=Genomics |volume=45 |issue= 1 |pages= 200-10 |year= 1997 |pmid= 9339377 |doi= 10.1006/geno.1997.4914 }}
* {{cite journal | vauthors = Gloeckner CJ, Mayerhofer PU, Landgraf P, Muntau AC, Holzinger A, Gerber JK, Kammerer S, Adamski J, Roscher AA | title = Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p | journal = Biochem. Biophys. Res. Commun. | volume = 271 | issue = 1 | pages = 144–50 | year = 2000 | pmid = 10777694 | doi = 10.1006/bbrc.2000.2572 }}
*{{cite journal | author=Götte K, Girzalsky W, Linkert M, ''et al.'' |title=Pex19p, a farnesylated protein essential for peroxisome biogenesis. |journal=Mol. Cell. Biol. |volume=18 |issue= 1 |pages= 616-28 |year= 1998 |pmid= 9418908 |doi=  }}
* {{cite journal | vauthors = Sugihara T, Kaul SC, Kato J, Reddel RR, Nomura H, Wadhwa R | title = Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway | journal = J. Biol. Chem. | volume = 276 | issue = 22 | pages = 18649–52 | year = 2001 | pmid = 11259404 | doi = 10.1074/jbc.C100011200 }}
*{{cite journal  | author=Matsuzono Y, Kinoshita N, Tamura S, ''et al.'' |title=Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 2116-21 |year= 1999 |pmid= 10051604 |doi=  }}
* {{cite journal | vauthors = Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP | title = Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences | journal = Mol. Cell. Biol. | volume = 21 | issue = 13 | pages = 4413–24 | year = 2001 | pmid = 11390669 | pmc = 87101 | doi = 10.1128/MCB.21.13.4413-4424.2001 }}
*{{cite journal | author=Sacksteder KA, Jones JM, South ST, ''et al.'' |title=PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. |journal=J. Cell Biol. |volume=148 |issue= 5 |pages= 931-44 |year= 2000 |pmid= 10704444 |doi= }}
* {{cite journal | vauthors = Biermanns M, Gärtner J | title = Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes | journal = Biochem. Biophys. Res. Commun. | volume = 285 | issue = 3 | pages = 649–55 | year = 2001 | pmid = 11453642 | doi = 10.1006/bbrc.2001.5220 }}
*{{cite journal | author=Gloeckner CJ, Mayerhofer PU, Landgraf P, ''et al.'' |title=Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p. |journal=Biochem. Biophys. Res. Commun. |volume=271 |issue= 1 |pages= 144-50 |year= 2000 |pmid= 10777694 |doi= 10.1006/bbrc.2000.2572 }}
* {{cite journal | vauthors = Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC | title = Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly | journal = Biochem. Biophys. Res. Commun. | volume = 291 | issue = 5 | pages = 1180–6 | year = 2002 | pmid = 11883941 | doi = 10.1006/bbrc.2002.6568 }}
*{{cite journal | author=Sugihara T, Kaul SC, Kato J, ''et al.'' |title=Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 18649-52 |year= 2001 |pmid= 11259404 |doi= 10.1074/jbc.C100011200 }}
* {{cite journal | vauthors = Fransen M, Brees C, Ghys K, Amery L, Mannaerts GP, Ladant D, Van Veldhoven PP | title = Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay | journal = Mol. Cell. Proteomics | volume = 1 | issue = 3 | pages = 243–52 | year = 2002 | pmid = 12096124 | doi = 10.1074/mcp.M100025-MCP200 }}
*{{cite journal | author=Fransen M, Wylin T, Brees C, ''et al.'' |title=Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences. |journal=Mol. Cell. Biol. |volume=21 |issue= 13 |pages= 4413-24 |year= 2001 |pmid= 11390669 |doi= 10.1128/MCB.21.13.4413-4424.2001 }}
* {{cite journal | vauthors = Ito M, Iidawa S, Izuka M, Haito S, Segawa H, Kuwahata M, Ohkido I, Ohno H, Miyamoto K | title = Interaction of a farnesylated protein with renal type IIa Na/Pi co-transporter in response to parathyroid hormone and dietary phosphate | journal = Biochem. J. | volume = 377 | issue = Pt 3 | pages = 607–16 | year = 2004 | pmid = 14558883 | pmc = 1223893 | doi = 10.1042/BJ20031223 }}
*{{cite journal | author=Biermanns M, Gärtner J |title=Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes. |journal=Biochem. Biophys. Res. Commun. |volume=285 |issue= 3 |pages= 649-55 |year= 2001 |pmid= 11453642 |doi= 10.1006/bbrc.2001.5220 }}
* {{cite journal | vauthors = Jones JM, Morrell JC, Gould SJ | title = PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins | journal = J. Cell Biol. | volume = 164 | issue = 1 | pages = 57–67 | year = 2004 | pmid = 14709540 | pmc = 2171958 | doi = 10.1083/jcb.200304111 }}
*{{cite journal | author=Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC |title=Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly. |journal=Biochem. Biophys. Res. Commun. |volume=291 |issue= 5 |pages= 1180-6 |year= 2002 |pmid= 11883941 |doi= 10.1006/bbrc.2002.6568 }}
* {{cite journal | vauthors = Muntau AC, Roscher AA, Kunau WH, Dodt G | title = Interaction of PEX3 and PEX19 visualized by fluorescence resonance energy transfer (FRET) | journal = Adv. Exp. Med. Biol. | volume = 544 | issue =  | pages = 221–4 | year = 2004 | pmid = 14713233 | doi = 10.1007/978-1-4419-9072-3_27 }}
*{{cite journal | author=Fransen M, Brees C, Ghys K, ''et al.'' |title=Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay. |journal=Mol. Cell Proteomics |volume=1 |issue= 3 |pages= 243-52 |year= 2002 |pmid= 12096124 |doi=  }}
* {{cite journal | vauthors = Fransen M, Vastiau I, Brees C, Brys V, Mannaerts GP, Van Veldhoven PP | title = Potential role for Pex19p in assembly of PTS-receptor docking complexes | journal = J. Biol. Chem. | volume = 279 | issue = 13 | pages = 12615–24 | year = 2004 | pmid = 14715663 | doi = 10.1074/jbc.M304941200 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Fang Y, Morrell JC, Jones JM, Gould SJ | title = PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins | journal = J. Cell Biol. | volume = 164 | issue = 6 | pages = 863–75 | year = 2004 | pmid = 15007061 | pmc = 2172291 | doi = 10.1083/jcb.200311131 }}
*{{cite journal | author=Ito M, Iidawa S, Izuka M, ''et al.'' |title=Interaction of a farnesylated protein with renal type IIa Na/Pi co-transporter in response to parathyroid hormone and dietary phosphate. |journal=Biochem. J. |volume=377 |issue= Pt 3 |pages= 607-16 |year= 2004 |pmid= 14558883 |doi= 10.1042/BJ20031223 }}
* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional Proteomics Mapping of a Human Signaling Pathway | journal = Genome Res. | volume = 14 | issue = 7 | pages = 1324–32 | year = 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
*{{cite journal | author=Jones JM, Morrell JC, Gould SJ |title=PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins. |journal=J. Cell Biol. |volume=164 |issue= 1 |pages= 57-67 |year= 2004 |pmid= 14709540 |doi= 10.1083/jcb.200304111 }}
* {{cite journal | vauthors = Shibata H, Kashiwayama Y, Imanaka T, Kato H | title = Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins | journal = J. Biol. Chem. | volume = 279 | issue = 37 | pages = 38486–94 | year = 2004 | pmid = 15252024 | doi = 10.1074/jbc.M402204200 }}
*{{cite journal | author=Muntau AC, Roscher AA, Kunau WH, Dodt G |title=Interaction of PEX3 and PEX19 visualized by fluorescence resonance energy transfer (FRET). |journal=Adv. Exp. Med. Biol. |volume=544 |issue=  |pages= 221-4 |year= 2004 |pmid= 14713233 |doi= }}
*{{cite journal | author=Fransen M, Vastiau I, Brees C, ''et al.'' |title=Potential role for Pex19p in assembly of PTS-receptor docking complexes. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12615-24 |year= 2004 |pmid= 14715663 |doi= 10.1074/jbc.M304941200 }}
*{{cite journal | author=Fang Y, Morrell JC, Jones JM, Gould SJ |title=PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. |journal=J. Cell Biol. |volume=164 |issue= 6 |pages= 863-75 |year= 2004 |pmid= 15007061 |doi= 10.1083/jcb.200311131 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal | author=Shibata H, Kashiwayama Y, Imanaka T, Kato H |title=Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins. |journal=J. Biol. Chem. |volume=279 |issue= 37 |pages= 38486-94 |year= 2004 |pmid= 15252024 |doi= 10.1074/jbc.M402204200 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
== External links ==
{{WikiDoc Sources}}
* [https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=pbd  GeneReviews/NCBI/NIH/UW entry on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum]
* [https://www.ncbi.nlm.nih.gov/omim/170993,202370,214100,266510,600279,600414,601498,601758,601789,601791,602136,602859,603164,603360,608666,170993,202370,214100,266510,600279,600414,601498,601758,601789,601791,602136,602859,603164,603360,608666 OMIM entries on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum]

Latest revision as of 17:58, 7 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene.[1][2][3]

Interactions

PEX19 has been shown to interact with:

References

  1. ↑ Kammerer S, Arnold N, Gutensohn W, Mewes HW, Kunau WH, Höfler G, Roscher AA, Braun A (November 1997). "Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein". Genomics. 45 (1): 200–10. doi:10.1006/geno.1997.4914. PMID 9339377.
  2. ↑ Matsuzono Y, Kinoshita N, Tamura S, Shimozawa N, Hamasaki M, Ghaedi K, Wanders RJ, Suzuki Y, Kondo N, Fujiki Y (April 1999). "Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly". Proc Natl Acad Sci U S A. 96 (5): 2116–21. doi:10.1073/pnas.96.5.2116. PMC 26746. PMID 10051604.
  3. ↑ "Entrez Gene: PEX19 peroxisomal biogenesis factor 19".
  4. ↑ 4.0 4.1 4.2 4.3 Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC (March 2002). "Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly". Biochem. Biophys. Res. Commun. 291 (5): 1180–6. doi:10.1006/bbrc.2002.6568. PMID 11883941.
  5. ↑ 5.0 5.1 5.2 Gloeckner CJ, Mayerhofer PU, Landgraf P, Muntau AC, Holzinger A, Gerber JK, Kammerer S, Adamski J, Roscher AA (April 2000). "Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p". Biochem. Biophys. Res. Commun. 271 (1): 144–50. doi:10.1006/bbrc.2000.2572. PMID 10777694.
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (March 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
  7. ↑ Biermanns M, Gärtner J (July 2001). "Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes". Biochem. Biophys. Res. Commun. 285 (3): 649–55. doi:10.1006/bbrc.2001.5220. PMID 11453642.
  8. ↑ 8.0 8.1 8.2 8.3 8.4 8.5 Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP (July 2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Mol. Cell. Biol. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMC 87101. PMID 11390669.
  9. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

External links

Retrieved from "https://www.wikidoc.org/index.php?title=PEX19&oldid=1410848"