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Oliguria is defined as a urine output that is less than 1 mL/kg/h in infants, less than 0.5 mL/kg/h in children, and less than 400 mL/day (equals 17mL/hour) in adults.<ref>{{cite journal | author = Klahr S, Miller S | title = Acute oliguria. | journal = N Engl J Med | volume = 338 | issue = 10 | pages = 671-5 | year = 1998 | id = PMID 9486997}} [http://content.nejm.org/cgi/content/full/338/10/671 Free Full Text].</ref>
Oliguria is defined as a urine output that is less than 1 mL/kg/h in infants, less than 0.5 mL/kg/h in children, and less than 400 mL/day (equals 17mL/hour) in adults.<ref>{{cite journal | author = Klahr S, Miller S | title = Acute oliguria. | journal = N Engl J Med | volume = 338 | issue = 10 | pages = 671-5 | year = 1998 | id = PMID 9486997}} [http://content.nejm.org/cgi/content/full/338/10/671 Free Full Text].</ref>


==Causes of Oliguria==
==Causes==
The mechanisms causing oliguria can be divided into several categories:
The mechanisms causing oliguria can be divided into several categories:



Revision as of 14:30, 25 February 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Decreased urine output; reduced urine output

Overview

Oliguria and anuria are the decreased or absent production of urine, respectively.

Oliguria is defined as a urine output that is less than 1 mL/kg/h in infants, less than 0.5 mL/kg/h in children, and less than 400 mL/day (equals 17mL/hour) in adults.[1]

Causes

The mechanisms causing oliguria can be divided into several categories:

Prerenal

In response to hypoperfusion of the kidney (e.g. as a result of dehydration by poor oral intake, diarrhea, massive bleeding or sepsis)

Renal

Due to kidney damage (severe hypoperfusion, rhabdomyolysis, medication)

Postrenal

As a consequence of obstruction of the urine flow (e.g. enlarged prostate, tumour compression urinary outflow, expanding hematoma or fluid collection)

The decreased production of urine may be a sign of dehydration, renal failure or urinary obstruction/urinary retention.

Postoperative oliguria

Patients usually have decrease in urine output after a major operation that may be a normal physiological response to:

  • Fluid/ blood loss – decreased glomerular filtration rate secondary to hypovolemia and/or hypotension
  • Response of adrenal cortex to stress -increase in aldosterone (Na and water retention) and antidiuretic hormone (ADH) release

Oliguria in infants

Oliguria, when defined as less than 1 mL/kg/h, in infants is not considered to be a reliable sign of renal failure.[2]

References

  1. Klahr S, Miller S (1998). "Acute oliguria". N Engl J Med. 338 (10): 671–5. PMID 9486997. Free Full Text.
  2. Arant B (1987). "Postnatal development of renal function during the first year of life". Pediatr Nephrol. 1 (3): 308–13. PMID 3153294.

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