Neurological symptoms in neonates

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differentiating Hypoglycemia from other Diseases that Cause Neurological Symptoms in Neonates:

Disease History and symptoms Investigations
Family History Lethargy and irritability Improvement of symptoms with glucose intake Fever Hepatomegaly
Hypoglycemia + + + - -
  • Blood glucose level
Sepsis - + - + -
  • Blood cultures
Inborn errors of metabolism + + - - +
  • Positive blood tests
Hyponatremia - + - - -
  • Plasma sodium falls below 125 mEq/L
Perinatal asphyxia + + - - -
  • MRI of acute brain injury confirms the diagnosis of encephalopathy

References

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