Neurocardiogenic syncope pathophysiology

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Neurocardiogenic Syncope Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Neurocardiogenic Syncope is defined as a syndrome in which triggering of a neural reflex results in a usually self-limited episode of systemic hypotension characterized by both bradycardia (asystole or relative bradycardia) and peripheral vasodilation. It is caused by an abnormal or exaggerated autonomic response to various stimuli which results from excessive autonomic reflex activity, which shows as abnormal vascular tone and heart rate. In contrast, Orthostatic Hypotension is a failure of the autonomic reflex response.