Multiple endocrine neoplasia type 2 physical examination: Difference between revisions
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{{ Multiple endocrine neoplasia type 2}} | {{ Multiple endocrine neoplasia type 2}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
Patients with multiple endocrine neoplasia type 2 usually appear tall with disproportionately elongated extremities. Physical examination of patients with multiple endocrine neoplasia type 2 is usually remarkable for episodic [[hypertension]], [[thyromegaly]], and [[anxiety]]. | Patients with multiple endocrine neoplasia type 2 usually appear tall with disproportionately elongated extremities. Physical examination of patients with multiple endocrine neoplasia type 2 is usually remarkable for episodic [[hypertension]], [[thyromegaly]], and [[anxiety]]. | ||
==Physical Examination== | ==Physical Examination== | ||
===Appearance of the Patient=== | ===Appearance of the Patient=== | ||
| Line 11: | Line 13: | ||
====Temperature==== | ====Temperature==== | ||
*A [[fever]] is often present | *A [[fever]] is often present | ||
====Pulse==== | ====Pulse==== | ||
=====Rate===== | =====Rate===== | ||
*[[Tachycardia]] | *[[Tachycardia]] | ||
=====Rhythm===== | =====Rhythm===== | ||
*The [[pulse]] is irregularly irregular | *The [[pulse]] is irregularly irregular | ||
====Blood Pressure==== | ====Blood Pressure==== | ||
*Episodic [[hypertension]] | *Episodic [[hypertension]] | ||
====Respiratory Rate==== | ====Respiratory Rate==== | ||
*[[Tachypnea]] may be present | *[[Tachypnea]] may be present | ||
===Skin=== | ===Skin=== | ||
* Swelling of neck | * Swelling of neck | ||
===Head=== | ===Head=== | ||
<gallery> | <gallery> | ||
| Line 27: | Line 36: | ||
Image:Neck swelling.jpg|On physical examination, she had goiter with large nodule in the right lobe of her thyroid gland.. <SMALL><SMALL>''<ref name="ShahnazariAghamaleki2012">{{cite journal|last1=Shahnazari|first1=Banafshe|last2=Aghamaleki|first2=Aria|last3=Larijani|first3=Bagher|last4=Mohajeri Tehrani|first4=Mohammad Reza|last5=Rafati|first5=Hasan|last6=Babamahmoodi|first6=Abdolreza|title=A Case of Multiple Endocrine Neoplasia Type 2B and Gangliomatosis of Gastrointestinal Tract|journal=Case Reports in Medicine|volume=2012|year=2012|pages=1–4|issn=1687-9627|doi=10.1155/2012/491054}}</ref> | Image:Neck swelling.jpg|On physical examination, she had goiter with large nodule in the right lobe of her thyroid gland.. <SMALL><SMALL>''<ref name="ShahnazariAghamaleki2012">{{cite journal|last1=Shahnazari|first1=Banafshe|last2=Aghamaleki|first2=Aria|last3=Larijani|first3=Bagher|last4=Mohajeri Tehrani|first4=Mohammad Reza|last5=Rafati|first5=Hasan|last6=Babamahmoodi|first6=Abdolreza|title=A Case of Multiple Endocrine Neoplasia Type 2B and Gangliomatosis of Gastrointestinal Tract|journal=Case Reports in Medicine|volume=2012|year=2012|pages=1–4|issn=1687-9627|doi=10.1155/2012/491054}}</ref> | ||
</gallery> | </gallery> | ||
===Eyes=== | ===Eyes=== | ||
* Numerous yellowish-white, sessile, painless nodules on the [[sclera]] and eyelids. | * Numerous yellowish-white, sessile, painless nodules on the [[sclera]] and eyelids. | ||
* Dry [[eye]]s may be present | * Dry [[eye]]s may be present | ||
===Neck=== | ===Neck=== | ||
* [[Lymph nodes]] | * [[Lymph nodes]] | ||
* [[Thyromegaly]] | * [[Thyromegaly]] | ||
* [[Dysphagia]] | * [[Dysphagia]] | ||
===Heart=== | ===Heart=== | ||
*A [[thrill]] may be present | *A [[thrill]] may be present | ||
===Neurologic=== | ===Neurologic=== | ||
* Mental status may be altered | * Mental status may be altered | ||
* [[Anxiety]] | * [[Anxiety]] | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category: | [[Category:Oncology]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 14:28, 21 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Patients with multiple endocrine neoplasia type 2 usually appear tall with disproportionately elongated extremities. Physical examination of patients with multiple endocrine neoplasia type 2 is usually remarkable for episodic hypertension, thyromegaly, and anxiety.
Physical Examination
Appearance of the Patient
- Patient may be tall and thin. Patient may have "marfanoid" body build with disproportionately elongated extremities.
Vitals
Temperature
- A fever is often present
Pulse
Rate
Rhythm
- The pulse is irregularly irregular
Blood Pressure
- Episodic hypertension
Respiratory Rate
- Tachypnea may be present
Skin
- Swelling of neck
Head
-
![The patient had mucosal neuromas on the anterior third of her tongue. Note the bumpy/blubbery lips [1]](/images/4/4c/Mucosal_neuromas_in_MEN_2.jpg)
The patient had mucosal neuromas on the anterior third of her tongue. Note the bumpy/blubbery lips [1]
-
![On physical examination, she had goiter with large nodule in the right lobe of her thyroid gland.. [1]](/images/5/58/Neck_swelling.jpg)
On physical examination, she had goiter with large nodule in the right lobe of her thyroid gland.. [1]
![The patient had mucosal neuromas on the anterior third of her tongue. Note the bumpy/blubbery lips [1]](/index.php/File:Mucosal_neuromas_in_MEN_2.jpg)
![On physical examination, she had goiter with large nodule in the right lobe of her thyroid gland.. [1]](/index.php/File:Neck_swelling.jpg)
Eyes
- Numerous yellowish-white, sessile, painless nodules on the sclera and eyelids.
- Dry eyes may be present
Neck
Heart
- A thrill may be present
Neurologic
- Mental status may be altered
- Anxiety
References
- ↑ 1.0 1.1 Shahnazari, Banafshe; Aghamaleki, Aria; Larijani, Bagher; Mohajeri Tehrani, Mohammad Reza; Rafati, Hasan; Babamahmoodi, Abdolreza (2012). "A Case of Multiple Endocrine Neoplasia Type 2B and Gangliomatosis of Gastrointestinal Tract". Case Reports in Medicine. 2012: 1–4. doi:10.1155/2012/491054. ISSN 1687-9627.