Multiple endocrine neoplasia type 2 other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Other diagnostic studies for multiple endocrine neoplasia type 2 include molecular [[genetic testing]] which include sequence analysis of select exons of mainly 10,11, 13-16 and sequence analysis of ''RET'' gene. | Other diagnostic studies for multiple endocrine neoplasia type 2 include molecular [[genetic testing]] which include sequence analysis of select exons of mainly 10,11, 13-16 and sequence analysis of [[RET proto-oncogene|''RET'' gene]]. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Molecular Genetic Testing=== | ===Molecular Genetic Testing=== | ||
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! style="background: #F5F5F5;" |A multi-gene panel | ! style="background: #F5F5F5;" |A multi-gene panel | ||
! style="background: #F5F5F5;" |''RET'' and other genes of interest | ! style="background: #F5F5F5;" |[[RET proto-oncogene|''RET'']] and other genes of interest | ||
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Revision as of 03:40, 5 October 2015
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Multiple endocrine neoplasia type 2 Microchapters |
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Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Other diagnostic studies for multiple endocrine neoplasia type 2 include molecular genetic testing which include sequence analysis of select exons of mainly 10,11, 13-16 and sequence analysis of RET gene.
Other Diagnostic Studies
Molecular Genetic Testing
| Test | Method |
|---|---|
| Select exon testing | Sequence analysis of select exons of mainly 10,11, 13-16 |
| Single-gene testing | Sequence analysis of RET gene |
| A multi-gene panel | RET and other genes of interest |
Histopathological Staining of the Biopsy
- Histopathological staining of medullary thyroid cancer[1]
- (1) Calcitonin: positive in tumor cells
- (2) Chromogranin: positive in tumor cells
- (3) Synaptophysin: positive in tumor cells
References
- ↑ Jessica Marquard & Charis Eng (1993). "Multiple Endocrine Neoplasia Type 2". PMID 020301434.