Multiple endocrine neoplasia type 2 other diagnostic studies: Difference between revisions
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===Histopathological Staining of the Biopsy=== | ===Histopathological Staining of the Biopsy=== | ||
* Histopathological staining of medullary thyroid cancer | * Histopathological staining of medullary thyroid cancer<ref>{{Cite journal| author = [[Jessica Marquard]] & [[Charis Eng]] | ||
| title = Multiple Endocrine Neoplasia Type 2 | |||
| year = 1993 | |||
| month = | |||
| pmid = 020301434 | |||
}}</ref> | |||
:(1) [[Calcitonin]]: positive in [[tumor]] [[cell]]s | :(1) [[Calcitonin]]: positive in [[tumor]] [[cell]]s | ||
:(2) [[Chromogranin]]: positive in [[tumor]] [[cell]]s | :(2) [[Chromogranin]]: positive in [[tumor]] [[cell]]s | ||
Revision as of 13:08, 29 September 2015
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Multiple endocrine neoplasia type 2 Microchapters |
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Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Other diagnostic studies for multiple endocrine neoplasia type 2 include molecular genetic testing which include sequence analysis of select exons of mainly 10,11, 13-16 and sequence analysis of RET gene.
Other Diagnostic Studies
Molecular Genetic Testing
| Test | Method |
|---|---|
| Select exon testing | Sequence analysis of select exons of mainly 10,11, 13-16 |
| Single-gene testing | Sequence analysis of RET gene |
| A multi-gene panel | RET and other genes of interest |
Histopathological Staining of the Biopsy
- Histopathological staining of medullary thyroid cancer[1]
- (1) Calcitonin: positive in tumor cells
- (2) Chromogranin: positive in tumor cells
- (3) Synaptophysin: positive in tumor cells
References
- ↑ Jessica Marquard & Charis Eng (1993). "Multiple Endocrine Neoplasia Type 2". PMID 020301434.