Multiple endocrine neoplasia type 1 electrocardiogram

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2] Ajay Gade MD[3]]

Overview

There are no specific ECG findings associated with Multiple endocrine neoplasia type-1. However, hypercalcemia secondary to hyperparathyroidism.

Electrocardiogram

There are no ECG findings associated with MEN-1. However, an ECG may be helpful in the diagnosis of cardiac complications of hypercalcemia. Findings on ECG are due to hypercalcemia and includes:[1]

  • ST segment - ST segment is short in patients with hypercalcemia when compared to normocalcemic patients. This represents a decrease in the systolic interval.
  • QRS complex - QRS complex has an increased amplitude in patients with hypercalcemia when compared to normocalcemic patients. This represents an increase in ventricular muscle mass.
  • T wave - T wave is prolonged in patients with hypercalcemia when compared to normocalcemic patients.

References

  1. Lind L, Ljunghall S (1994). "Serum calcium and the ECG in patients with primary hyperparathyroidism". J Electrocardiol. 27 (2): 99–103. doi:10.1016/S0022-0736(05)80092-5. PMID 8201301.

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