Multiple endocrine neoplasia type 1 MRI: Difference between revisions
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{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
[[MRI]] may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. | [[MRI]] may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. Findings on MRI suggestive of multiple endocrine neoplasia type 1 include diffuse heterogenous enhancement of T1 C+ (Gd), low T1 signal and high T2 signal. | ||
==MRI== | ==MRI== | ||
===Gastrointestinal Neuroendocrine Tumors=== | ===Gastrointestinal Neuroendocrine Tumors=== | ||
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* Smaller [[lesion]]s may be difficult to [[diagnose]]. | * Smaller [[lesion]]s may be difficult to [[diagnose]]. | ||
* Signal characteristics of larger lesion include:<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref> | * Signal characteristics of larger lesion include:<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref> | ||
:* '''T1''': low signal | :* '''T1''': low signal | ||
:* '''T2''': high signal | :* '''T2''': high signal | ||
:* '''T1 (C+) Gd''': most show early diffuse heterogenous enhancement | :* '''T1 (C+) Gd''': most show early diffuse heterogenous enhancement | ||
==Reference== | ==Reference== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Hereditary cancers]] | [[Category:Hereditary cancers]] |
Revision as of 19:30, 18 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1. Findings on MRI suggestive of multiple endocrine neoplasia type 1 include diffuse heterogenous enhancement of T1 C+ (Gd), low T1 signal and high T2 signal.
MRI
Gastrointestinal Neuroendocrine Tumors
- MRI is used for suspected hepatic, pancreatic or retroperitoneal neuroendocrine tumors, often with gadolinium contrast.[1]
- MRI enterography is also possible
Insulinoma
- Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumors[2]
- MRI findings of insulinoma include the following:[3]
Somatostatinoma
- T1: low signal
- T2: high signal
- T1 (C+) Gd: most show early diffuse heterogenous enhancement
Reference
- ↑ "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
- ↑ "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
- ↑ "Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]".