Multiple endocrine neoplasia type 1 MRI: Difference between revisions
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{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1. | [[MRI]] may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. | ||
==MRI== | ==MRI== | ||
===Gastrointestinal Neuroendocrine Tumors<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref>=== | ===Gastrointestinal Neuroendocrine Tumors<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref>=== | ||
* MRI isw used for suspected hepatic, pancreatic or retroperitoneal neuroendocrine | * [[MRI]] isw used for suspected hepatic, pancreatic or retroperitoneal [[neuroendocrine tumor]]s, often with [[gadolinium]] contrast. | ||
* MRI enterography is also possible. | * [[MRI]] [[enterography]] is also possible. | ||
===Insulinoma<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref>=== | ===Insulinoma<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref>=== | ||
* Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these | * Dynamic [[MRI]] with fast gradient [[echo]] sequences following [[bolus]] [[injection]] of [[contrast]] medium may aid the detection of these [[tumor]]s<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319 }} </ref> | ||
* '''T1 C+ (Gd)''': typically shows enhancement, although contrast enhancement may not improve | * '''T1 C+ (Gd)''': typically shows enhancement, although [[contrast]] enhancement may not improve [[tumor]] visualisation compared with non-[[contrast]] images | ||
===Somatostatinoma<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref>=== | ===Somatostatinoma<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref>=== | ||
* Smaller | * Smaller [[lesion]]s may be difficult to [[diagnose]]. | ||
* Signal characteristics of larger lesion include: | * Signal characteristics of larger lesion include: | ||
:* '''T1''': low signal 1,8 | :* '''T1''': low signal 1,8 | ||
:* '''T2''': high signal 1,8 | :* '''T2''': high signal 1,8 | ||
:* '''T1 (C+) Gd''': most show early diffuse heterogenous enhancement | :* '''T1 (C+) Gd''': most show early diffuse heterogenous enhancement | ||
==Reference== | ==Reference== | ||
{{Reflist}} | {{Reflist}} | ||
[[Category:Hereditary cancers]] | [[Category:Hereditary cancers]] |
Revision as of 11:35, 11 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1.
MRI
Gastrointestinal Neuroendocrine Tumors[1]
- MRI isw used for suspected hepatic, pancreatic or retroperitoneal neuroendocrine tumors, often with gadolinium contrast.
- MRI enterography is also possible.
Insulinoma[2]
- Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumors[3]
- T1 C+ (Gd): typically shows enhancement, although contrast enhancement may not improve tumor visualisation compared with non-contrast images
Somatostatinoma[4]
- T1: low signal 1,8
- T2: high signal 1,8
- T1 (C+) Gd: most show early diffuse heterogenous enhancement
Reference
- ↑ "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
- ↑ "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
- ↑ "Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]".