Multiple endocrine neoplasia type 1 MRI: Difference between revisions

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===Insulinoma<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref>===
===Insulinoma<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref>===
* Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumors<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319  }} </ref>
* Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumors<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319  }} </ref>
* T1 C+ (Gd): typically shows enhancement, although contrast enhancement may not improve tumour visualisation compared with non-contrast images
* '''T1 C+ (Gd)''': typically shows enhancement, although contrast enhancement may not improve tumour visualisation compared with non-contrast images


===Somatostatinoma<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref>===
===Somatostatinoma<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref>===

Revision as of 11:34, 11 September 2015

Multiple endocrine neoplasia type 1 Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1.

MRI

Gastrointestinal Neuroendocrine Tumors[1]

  • MRI isw used for suspected hepatic, pancreatic or retroperitoneal neuroendocrine tumors, often with gadolinium contrast.
  • MRI enterography is also possible.

Insulinoma[2]

  • Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumors[3]
  • T1 C+ (Gd): typically shows enhancement, although contrast enhancement may not improve tumour visualisation compared with non-contrast images

Somatostatinoma[4]

  • Smaller lesions may be difficult to diagnose.
  • Signal characteristics of larger lesion include:
  • T1: low signal 1,8
  • T2: high signal 1,8
  • T1 (C+) Gd: most show early diffuse heterogenous enhancement

Reference

  1. "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
  2. "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
  3. Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
  4. "Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]".