Multiple endocrine neoplasia type 1 (patient information): Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 22: | Line 22: | ||
* [[Anorexia]] | * [[Anorexia]] | ||
==What causes multiple endocrine neoplasia type 1?== | ==What causes multiple endocrine neoplasia type 1?== | ||
* MEN1 is an inherited disorder that causes | * MEN1 is an inherited disorder that causes [[tumor]]s in the [[endocrine gland]]s and the [[duodenum]], the first part of the [[small intestine]]. Genetic [[mutation]]s is speculated to be the cause of the [[disease]]. | ||
==Who is at highest risk?== | ==Who is at highest risk?== | ||
* Age <40 years | * Age <40 years | ||
* Positive family history | * Positive family history | ||
* Multifocal or recurrent neoplasia | * Multifocal or recurrent [[neoplasia]] | ||
* Two or more organ systems tumor involvement | * Two or more [[organ]] systems [[tumor]] involvement | ||
==Diagnosis== | ==Diagnosis== | ||
* MEN1 is detected by gene testing or, when gene testing is unavailable or yields a negative result, by laboratory tests that measure hormone levels. Less often, MEN1 is diagnosed based on an individual's medical and family history. | * MEN1 is detected by [[gene]] testing or, when [[gene]] testing is unavailable or yields a negative result, by laboratory tests that measure [[hormone]] levels. Less often, MEN1 is diagnosed based on an individual's medical and [[family history]]. | ||
==When to seek urgent medical care?== | ==When to seek urgent medical care?== | ||
* Seek urgent medical care if there are symptoms of MEN 1 or its complications. | * Seek urgent medical care if there are symptoms of MEN 1 or its complications. | ||
==Treatment options== | ==Treatment options== | ||
* MEN1 cannot be cured, but regular testing can detect the problems caused by MEN1 | * MEN1 cannot be cured, but regular testing can detect the problems caused by MEN1 [[tumor]]s many years before serious complications develop. Careful monitoring enables doctors to adjust an individual's treatment as needed. | ||
==Where to find medical care for multiple endocrine neoplasia type 1?== | ==Where to find medical care for multiple endocrine neoplasia type 1?== | ||
| Line 44: | Line 43: | ||
==Prevention== | ==Prevention== | ||
* Screening people with family history of MEN 1 is recommended. | * Screening people with family history of MEN 1 is recommended. | ||
==What to expect (Outlook/Prognosis)?== | ==What to expect (Outlook/Prognosis)?== | ||
* Most people with MEN1 have a long and productive life. | * Most people with MEN1 have a long and productive life. | ||
* Most of the | * Most of the [[tumor]]s are [[benign]] while some [[pancreatic tumor]]s may become cancerous and lower life expectancy. | ||
==Possible complications== | ==Possible complications== | ||
* [[Stomach]] or [[intestinal ulcer]]s | |||
* Stomach or intestinal | * [[Galactorrhea]] | ||
* Galactorrhea | * [[Infertility]] | ||
* [[Impotency]] | |||
* Infertility | |||
* Impotency | |||
==Sources== | ==Sources== | ||
* http://www.niddk.nih.gov/health-information/health-topics/endocrine/multiple-endocrine-neoplasia-type-1/Pages/fact-sheet.aspx | * http://www.niddk.nih.gov/health-information/health-topics/endocrine/multiple-endocrine-neoplasia-type-1/Pages/fact-sheet.aspx | ||
* https://www.nlm.nih.gov/medlineplus/ency/article/000398.htm | * https://www.nlm.nih.gov/medlineplus/ency/article/000398.htm | ||
Revision as of 14:58, 4 September 2015
For the WikiDoc page for this topic, click here.
|
Multiple endocrine neoplasia type 1 |
|
Where to find medical care for Multiple endocrine neoplasia type 1? |
|---|
|
Multiple endocrine neoplasia type 1 On the Web |
|
Directions to Hospitals Treating Multiple endocrine neoplasia type 1 |
|
Risk calculators and risk factors for Multiple endocrine neoplasia type 1 |
Template:WikiDoc Sources
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
- Multiple endocrine neoplasia (MEN) type I is a disease passed down through families, in which one or more of the endocrine glands are overactive or form a tumor. Endocrine glands most commonly involved include pancreas, parathyroid and pituitary.
What are the symptoms of multiple endocrine neoplasia type 1?
- Visual disturbance
- Headache
- Constipation
- Nausea
- Vomiting
- Polyuria
- Dehydration
- Hypercalciuria
- Hypertension
- Shortened QT interval
- Lethargy
- Depression
- Confusion
- Anorexia
What causes multiple endocrine neoplasia type 1?
- MEN1 is an inherited disorder that causes tumors in the endocrine glands and the duodenum, the first part of the small intestine. Genetic mutations is speculated to be the cause of the disease.
Who is at highest risk?
- Age <40 years
- Positive family history
- Multifocal or recurrent neoplasia
- Two or more organ systems tumor involvement
Diagnosis
- MEN1 is detected by gene testing or, when gene testing is unavailable or yields a negative result, by laboratory tests that measure hormone levels. Less often, MEN1 is diagnosed based on an individual's medical and family history.
When to seek urgent medical care?
- Seek urgent medical care if there are symptoms of MEN 1 or its complications.
Treatment options
- MEN1 cannot be cured, but regular testing can detect the problems caused by MEN1 tumors many years before serious complications develop. Careful monitoring enables doctors to adjust an individual's treatment as needed.
Where to find medical care for multiple endocrine neoplasia type 1?
Directions to Hospitals Treating Multiple endocrine neoplasia type 1
Prevention
- Screening people with family history of MEN 1 is recommended.
What to expect (Outlook/Prognosis)?
- Most people with MEN1 have a long and productive life.
- Most of the tumors are benign while some pancreatic tumors may become cancerous and lower life expectancy.