Mononeuritis multiplex

Mononeuritis multiplex
ICD-10	G58.7
ICD-9	354.5
DiseasesDB	8346
MedlinePlus	000782
eMedicine	pmr/80
MeSH	D020422

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Mononeuritis multiplex is the clinical picture that arises from problems with multiple individual nerves serially or almost simultaneously.

Synonyms

Mononeuropathy multiplex

Clinical findings

Mononeuritis multiplex typically presents with the acute or subacute evolution of loss of sensory and motor function of individual peripheral nerves. The pattern of involvement is asymmetric.

Diagnosis

Electrodiagnostic studies will show multifocal sensory motor axonal neuropathy.

Causes and associations

• diabetes mellitus
• vasculitis
  • polyarteritis nodosa
  • Wegener granulomatosis
  • Churg-Strauss syndrome
• immune-mediated diseases
  • rheumatoid arthritis
  • SLE
  • sarcoidosis
• infections
  • leprosy
  • Lyme disease
  • HIV
• amyloidosis
• cryoglobulinemia