Molluscum contagiosum historical perspective

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Molluscum contagiosum Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Molluscum contagiosum from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic criteria

History and Symptoms

Physical Examination

Laboratory Findings

X ray

Ultrasound

CT Scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis. In 1841 Paterson demonstrated molluscum contagiosum infectious nature.The viral nature of the disease demonstrated by Juliusberg in 1905. Outbreaks have occurred in the different settings like swimming pools, but the exact information about outbreaks is not available due report policy.

Discovery

Molluscum contagiosum was first discovered by Bateman in 1817.[1]

Landmark Events in the Development of Treatment Strategies

  • Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.[1]
  • In 1841 Paterson demonstrated molluscum contagiosum infectious nature.
  • The molluscum or Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were also described by Henderson and Paterson in 1841.[2]
  • The viral nature of the disease demonstrated by Juliusberg in 1905.[3]
  • Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.[4]

Impact on Cultural History

  • An outbreak of Molluscum contagiosum has been reported in a small rural community. The outbreak infected 34 patients, most of them were children between 9-18 years old. Rsearchers reported the spread as a result of direct contact and by fomites.[5]
  • Outbreaks have occurred in the following settings:
    • Swimming pools (in children)
    • Wrestling matches
    • During surgery, by a surgeon with a hand lesion
    • Via tattoos (although rarely)
    • Sexually: MC can be sexually transmitted but not all genital lesions are sexually transmitted.[6]

References

  1. 1.0 1.1 Pickering WR, Woods RA (1972). "The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine". Biochim. Biophys. Acta. 264 (1): 45–58. PMID 4336666.
  2. Torres A (1986). "The molluscum body. The Henderson-Paterson body with Lipschütz granules". Am J Dermatopathol. 8 (3): 260–2. PMID 3524303.
  3. RAKE G, BLANK H (1950). "The relationship of host and virus in molluscum contagiosum". J. Invest. Dermatol. 15 (2): 81–93. PMID 15437050.
  4. "www.microbiologyresearch.org" (PDF).
  5. Oren B, Wende SO (1991). "An outbreak of molluscum contagiosum in a kibbutz". Infection. 19 (3): 159–61. PMID 1889869.
  6. "Molluscum Contagiosum - Oklahoma State Department of Health".