Molluscum contagiosum historical perspective: Difference between revisions
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* In 1841 Paterson demonstrated molluscum contagiosum infectious nature. | * In 1841 Paterson demonstrated molluscum contagiosum infectious nature. | ||
* The molluscum or Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were also described by Henderson and Paterson in 1841.<ref name="pmid3524303">{{cite journal |vauthors=Torres A |title=The molluscum body. The Henderson-Paterson body with Lipschütz granules |journal=Am J Dermatopathol |volume=8 |issue=3 |pages=260–2 |year=1986 |pmid=3524303 |doi= |url=}}</ref> | * The molluscum or Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were also described by Henderson and Paterson in 1841.<ref name="pmid3524303">{{cite journal |vauthors=Torres A |title=The molluscum body. The Henderson-Paterson body with Lipschütz granules |journal=Am J Dermatopathol |volume=8 |issue=3 |pages=260–2 |year=1986 |pmid=3524303 |doi= |url=}}</ref> | ||
* The viral nature of the disease demonstrated by Juliusberg in 1905.<ref name="pmid15437050">{{cite journal |vauthors=RAKE G, BLANK H |title=The relationship of host and virus in molluscum contagiosum |journal=J. Invest. Dermatol. |volume=15 |issue=2 |pages=81–93 |year=1950 |pmid=15437050 |doi= |url=}}</ref> | * The viral nature of the disease was demonstrated by Juliusberg in 1905.<ref name="pmid15437050">{{cite journal |vauthors=RAKE G, BLANK H |title=The relationship of host and virus in molluscum contagiosum |journal=J. Invest. Dermatol. |volume=15 |issue=2 |pages=81–93 |year=1950 |pmid=15437050 |doi= |url=}}</ref> | ||
* Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.<ref name="urlwww.microbiologyresearch.org">{{cite web |url=http://www.microbiologyresearch.org/docserver/fulltext/jgv/65/5/JV0650050875.pdf?expires=1496763006&id=id&accname=guest&checksum=3F95D045A98BEE2DC076E265C060AC3E |title=www.microbiologyresearch.org |format= |work= |accessdate=}}</ref> | * Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive [[Endonucleases|endonuclease]] analysis of the [[Genome|genomes]] of isolates.<ref name="urlwww.microbiologyresearch.org">{{cite web |url=http://www.microbiologyresearch.org/docserver/fulltext/jgv/65/5/JV0650050875.pdf?expires=1496763006&id=id&accname=guest&checksum=3F95D045A98BEE2DC076E265C060AC3E |title=www.microbiologyresearch.org |format= |work= |accessdate=}}</ref> | ||
== | ==Outbreaks== | ||
* An outbreak of Molluscum contagiosum has been reported in a small rural community. The outbreak infected 34 patients, most of them were children between 9-18 years old. | * An outbreak of Molluscum contagiosum has been reported in a small rural community. The outbreak infected 34 patients, which most of them were children between 9-18 years old. Researchers reported the spread as a result of direct contact and by fomites.<ref name="pmid1889869">{{cite journal |vauthors=Oren B, Wende SO |title=An outbreak of molluscum contagiosum in a kibbutz |journal=Infection |volume=19 |issue=3 |pages=159–61 |year=1991 |pmid=1889869 |doi= |url=}}</ref> | ||
* Outbreaks have occurred in the following settings: | * Outbreaks during history have occurred in the following settings: | ||
** Swimming pools (in children) | ** Swimming pools (in children) | ||
** Wrestling matches | ** Wrestling matches | ||
Revision as of 14:24, 12 June 2017
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Molluscum contagiosum Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]
Overview
Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis. In 1841 Paterson demonstrated molluscum contagiosum infectious nature.The viral nature of the disease demonstrated by Juliusberg in 1905. Outbreaks have occurred in the different settings like swimming pools, but the exact information about outbreaks is not available due to report policy.
Discovery
Molluscum contagiosum was first discovered by Bateman in 1817.[1]
Landmark Events in the Development of Treatment Strategies
- Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.[1]
- In 1841 Paterson demonstrated molluscum contagiosum infectious nature.
- The molluscum or Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were also described by Henderson and Paterson in 1841.[2]
- The viral nature of the disease was demonstrated by Juliusberg in 1905.[3]
- Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.[4]
Outbreaks
- An outbreak of Molluscum contagiosum has been reported in a small rural community. The outbreak infected 34 patients, which most of them were children between 9-18 years old. Researchers reported the spread as a result of direct contact and by fomites.[5]
- Outbreaks during history have occurred in the following settings:
- Swimming pools (in children)
- Wrestling matches
- During surgery, by a surgeon with a hand lesion
- Via tattoos (although rarely)
- Sexually: MC can be sexually transmitted but not all genital lesions are sexually transmitted.[6]
References
- ↑ 1.0 1.1 Pickering WR, Woods RA (1972). "The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine". Biochim. Biophys. Acta. 264 (1): 45–58. PMID 4336666.
- ↑ Torres A (1986). "The molluscum body. The Henderson-Paterson body with Lipschütz granules". Am J Dermatopathol. 8 (3): 260–2. PMID 3524303.
- ↑ RAKE G, BLANK H (1950). "The relationship of host and virus in molluscum contagiosum". J. Invest. Dermatol. 15 (2): 81–93. PMID 15437050.
- ↑ "www.microbiologyresearch.org" (PDF).
- ↑ Oren B, Wende SO (1991). "An outbreak of molluscum contagiosum in a kibbutz". Infection. 19 (3): 159–61. PMID 1889869.
- ↑ "Molluscum Contagiosum - Oklahoma State Department of Health".