Merkel cell cancer CT: Difference between revisions
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{{CMG}} {{AE}} {{VKG}} | {{CMG}} {{AE}} {{VKG}} | ||
==Overview== | ==Overview== | ||
[[Computed tomography|CT scan]] is useful in detecting [[metastasis]] to organs and regional lymph nodes in | [[Computed tomography|CT scan]] is useful in detecting [[metastasis]] to organs and regional lymph nodes in merkel cell carcinoma. | ||
==Key CT findings in Merkel cell cancer== | ==Key CT findings in Merkel cell cancer== | ||
*[[Computed tomography|CT scan]] of the [[chest]] and [[abdomen]] may use to detect | *[[Computed tomography|CT scan]] of the [[chest]] and [[abdomen]] may use to detect merkel cell carcinoma [[metastasis]].<ref name="PeloschekNovotny2010">{{cite journal|last1=Peloschek|first1=Philipp|last2=Novotny|first2=Clemens|last3=Mueller-Mang|first3=Christina|last4=Weber|first4=Michael|last5=Sailer|first5=Johannes|last6=Dawid|first6=Markus|last7=Czerny|first7=Christian|last8=Dudczak|first8=Robert|last9=Kletter|first9=Kurt|last10=Becherer|first10=Alexander|title=Diagnostic imaging in Merkel cell carcinoma: Lessons to learn from 16 cases with correlation of sonography, CT, MRI and PET|journal=European Journal of Radiology|volume=73|issue=2|year=2010|pages=317–323|issn=0720048X|doi=10.1016/j.ejrad.2008.10.032}}</ref> | ||
*[[Computed tomography|CT scan]] of the [[abdomen]] may shows the following:<ref name="NguyenMcCullough2002">{{cite journal|last1=Nguyen|first1=Ba D.|last2=McCullough|first2=Ann E.|title=Imaging of Merkel Cell Carcinoma|journal=RadioGraphics|volume=22|issue=2|year=2002|pages=367–376|issn=0271-5333|doi=10.1148/radiographics.22.2.g02mr14367}}</ref><ref name="GollubGruen1996">{{cite journal|last1=Gollub|first1=M J|last2=Gruen|first2=D R|last3=Dershaw|first3=D D|title=Merkel cell carcinoma: CT findings in 12 patients.|journal=American Journal of Roentgenology|volume=167|issue=3|year=1996|pages=617–620|issn=0361-803X|doi=10.2214/ajr.167.3.8751663}}</ref><ref name="ColganTarantola2012">{{cite journal|last1=Colgan|first1=Michael B.|last2=Tarantola|first2=Tina I.|last3=Weaver|first3=Amy L.|last4=Wiseman|first4=Gregory A.|last5=Roenigk|first5=Randall K.|last6=Brewer|first6=Jerry D.|last7=Otley|first7=Clark C.|title=The predictive value of imaging studies in evaluating regional lymph node involvement in Merkel cell carcinoma|journal=Journal of the American Academy of Dermatology|volume=67|issue=6|year=2012|pages=1250–1256|issn=01909622|doi=10.1016/j.jaad.2012.03.018}}</ref><ref name="LuFleming2012">{{cite journal|last1=Lu|first1=Yang|last2=Fleming|first2=Stephen E.|last3=Fields|first3=Ryan C.|last4=Coit|first4=Daniel G.|last5=Carrasquillo|first5=Jorge A.|title=Comparison of 18F-FDG PET/CT and 111In Pentetreotide Scan for Detection of Merkel Cell Carcinoma|journal=Clinical Nuclear Medicine|volume=37|issue=8|year=2012|pages=759–762|issn=0363-9762|doi=10.1097/RLU.0b013e31825ae8e7}}</ref> | *[[Computed tomography|CT scan]] of the [[abdomen]] may shows the following:<ref name="NguyenMcCullough2002">{{cite journal|last1=Nguyen|first1=Ba D.|last2=McCullough|first2=Ann E.|title=Imaging of Merkel Cell Carcinoma|journal=RadioGraphics|volume=22|issue=2|year=2002|pages=367–376|issn=0271-5333|doi=10.1148/radiographics.22.2.g02mr14367}}</ref><ref name="GollubGruen1996">{{cite journal|last1=Gollub|first1=M J|last2=Gruen|first2=D R|last3=Dershaw|first3=D D|title=Merkel cell carcinoma: CT findings in 12 patients.|journal=American Journal of Roentgenology|volume=167|issue=3|year=1996|pages=617–620|issn=0361-803X|doi=10.2214/ajr.167.3.8751663}}</ref><ref name="ColganTarantola2012">{{cite journal|last1=Colgan|first1=Michael B.|last2=Tarantola|first2=Tina I.|last3=Weaver|first3=Amy L.|last4=Wiseman|first4=Gregory A.|last5=Roenigk|first5=Randall K.|last6=Brewer|first6=Jerry D.|last7=Otley|first7=Clark C.|title=The predictive value of imaging studies in evaluating regional lymph node involvement in Merkel cell carcinoma|journal=Journal of the American Academy of Dermatology|volume=67|issue=6|year=2012|pages=1250–1256|issn=01909622|doi=10.1016/j.jaad.2012.03.018}}</ref><ref name="LuFleming2012">{{cite journal|last1=Lu|first1=Yang|last2=Fleming|first2=Stephen E.|last3=Fields|first3=Ryan C.|last4=Coit|first4=Daniel G.|last5=Carrasquillo|first5=Jorge A.|title=Comparison of 18F-FDG PET/CT and 111In Pentetreotide Scan for Detection of Merkel Cell Carcinoma|journal=Clinical Nuclear Medicine|volume=37|issue=8|year=2012|pages=759–762|issn=0363-9762|doi=10.1097/RLU.0b013e31825ae8e7}}</ref> | ||
**[[Retroperitoneal]] and peripancreatic [[adenopathy]] | **[[Retroperitoneal]] and peripancreatic [[adenopathy]] | ||
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**Involvement of the [[gut]] | **Involvement of the [[gut]] | ||
** | ** | ||
*[[Computed tomography|CT scan]] of the [[head]] and [[neck]] may be also used to find | *[[Computed tomography|CT scan]] of the [[head]] and [[neck]] may be also used to find merkel cell carcinoma that has spread to regional [[lymph nodes]]. | ||
*[[Computed tomography|CT scan]] of the [[head]] may demonstrates a [[soft-tissue]] [[Nodule (medicine)|nodule]] in | *[[Computed tomography|CT scan]] of the [[head]] may demonstrates a [[soft-tissue]] [[Nodule (medicine)|nodule]] in merkel cell carcinoma. | ||
*[[Computed tomography|CT scan]] in patients with | *[[Computed tomography|CT scan]] in patients with merkel cell carcinoma helps with [[Cancer staging|staging]] of the disease.<ref name="pmid8751663">{{cite journal |vauthors=Gollub MJ, Gruen DR, Dershaw DD |title=Merkel cell carcinoma: CT findings in 12 patients |journal=AJR Am J Roentgenol |volume=167 |issue=3 |pages=617–20 |date=September 1996 |pmid=8751663 |doi=10.2214/ajr.167.3.8751663 |url=}}</ref> | ||
[[File:Metastatic-merkel-cell-carcinoma.jpg|center|thumb|Case courtesy of Dr Anna Margherita Maffione, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/33259">rID: 33259</a>]] | [[File:Metastatic-merkel-cell-carcinoma.jpg|center|thumb|Case courtesy of Dr Anna Margherita Maffione, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/33259">rID: 33259</a>]] | ||
Latest revision as of 03:01, 31 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
CT scan is useful in detecting metastasis to organs and regional lymph nodes in merkel cell carcinoma.
Key CT findings in Merkel cell cancer
- CT scan of the chest and abdomen may use to detect merkel cell carcinoma metastasis.[1]
- CT scan of the abdomen may shows the following:[2][3][4][5]
- Retroperitoneal and peripancreatic adenopathy
- Involvement of the lower left anterior chest wall
- Involvement of the ribs
- Involvement of the gut
- CT scan of the head and neck may be also used to find merkel cell carcinoma that has spread to regional lymph nodes.
- CT scan of the head may demonstrates a soft-tissue nodule in merkel cell carcinoma.
- CT scan in patients with merkel cell carcinoma helps with staging of the disease.[6]
References
- ↑ Peloschek, Philipp; Novotny, Clemens; Mueller-Mang, Christina; Weber, Michael; Sailer, Johannes; Dawid, Markus; Czerny, Christian; Dudczak, Robert; Kletter, Kurt; Becherer, Alexander (2010). "Diagnostic imaging in Merkel cell carcinoma: Lessons to learn from 16 cases with correlation of sonography, CT, MRI and PET". European Journal of Radiology. 73 (2): 317–323. doi:10.1016/j.ejrad.2008.10.032. ISSN 0720-048X.
- ↑ Nguyen, Ba D.; McCullough, Ann E. (2002). "Imaging of Merkel Cell Carcinoma". RadioGraphics. 22 (2): 367–376. doi:10.1148/radiographics.22.2.g02mr14367. ISSN 0271-5333.
- ↑ Gollub, M J; Gruen, D R; Dershaw, D D (1996). "Merkel cell carcinoma: CT findings in 12 patients". American Journal of Roentgenology. 167 (3): 617–620. doi:10.2214/ajr.167.3.8751663. ISSN 0361-803X.
- ↑ Colgan, Michael B.; Tarantola, Tina I.; Weaver, Amy L.; Wiseman, Gregory A.; Roenigk, Randall K.; Brewer, Jerry D.; Otley, Clark C. (2012). "The predictive value of imaging studies in evaluating regional lymph node involvement in Merkel cell carcinoma". Journal of the American Academy of Dermatology. 67 (6): 1250–1256. doi:10.1016/j.jaad.2012.03.018. ISSN 0190-9622.
- ↑ Lu, Yang; Fleming, Stephen E.; Fields, Ryan C.; Coit, Daniel G.; Carrasquillo, Jorge A. (2012). "Comparison of 18F-FDG PET/CT and 111In Pentetreotide Scan for Detection of Merkel Cell Carcinoma". Clinical Nuclear Medicine. 37 (8): 759–762. doi:10.1097/RLU.0b013e31825ae8e7. ISSN 0363-9762.
- ↑ Gollub MJ, Gruen DR, Dershaw DD (September 1996). "Merkel cell carcinoma: CT findings in 12 patients". AJR Am J Roentgenol. 167 (3): 617–20. doi:10.2214/ajr.167.3.8751663. PMID 8751663.