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== Causes==
== Causes==
=== Life Threatening Causes===
=== Life Threatening Causes===
Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.


*[[Life threatening cause 1]]
* Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.
*[[Life threatening cause 2]]
* Most acute causes of amnesia are considered life-threatening, among them, are the following:
*[[Life threatening cause 3]]
**Electrolyte imbalances
**Head trauma
**Hypoglycemia
**Infections


=== Common Causes===
=== Common Causes===


*[[Common cause 1]]
*Alzheimer
*[[Common cause 2]]
*Vascular dementia
*[[Common cause 3]]
*Frontotemporal dementia
*[[Common cause 4]]
*Vitamin deficiency
*[[Common cause 5]]
*Depression


==Diagnosis==
==Diagnosis==
Shown below is an algorithm summarizing the diagnosis of amnesia according the the American Academy of Neurology guidelines.  
Shown below is an algorithm summarizing the diagnosis of amnesia according to the the American Academy of Neurology guidelines.  


{{familytree/start |summary=PE diagnosis Algorithm.}}  
{{familytree/start |summary=PE diagnosis Algorithm.}}  
{{familytree | | | | | | | | A01 |A01= Patient with amnesia}} {{familytree | | | | |,|-|-|-|^|-|-|-|-|.| | | }}  
{{familytree | | | | | | | | A01 |A01= Patient with amnesia}} {{familytree | | | | |,|-|-|-|^|-|-|-|-|.| | | }}  
{{familytree | | | B01 | | | | | | | | B02 | | |B01= Acute onset|B02= Chronic onset}}  
{{familytree | | | B01 | | | | | | | | B02 | | |B01= Acute onset|B02= Chronic onset}}  
{{familytree | | | |!| | | | | | | | | |!| | | | }}
{{familytree | | | |!| | | | | | | | | B01 |-| B02 |-| B03 |-| B04| | |B01= Measure vitamin B12, and folic acid, and TSH |B02= Abnormal?|B03= Yes|B04= Vitamin deficiency, hypothyroidism}}
{{familytree | | | |!| | | | | | | | | |!| | | | }}
{{familytree | | | |!| | | | | | | | | |!| | | | }}
{{familytree | | | B01 | | | | | | | | B02 |-| B03 |-| B04 | | |B01= Fluctuating course, inattention, disorganized thinking,
{{familytree | | | B01 | | | | | | | | B02 |-| B03 |-| B04 | | |B01= Fluctuating course, inattention, disorganized thinking,
Line 41: Line 45:
{{familytree | | |B01| | B02 | | | | |!| | | | B01= No|B02= Concussion, post-concussive amnesia}}
{{familytree | | |B01| | B02 | | | | |!| | | | B01= No|B02= Concussion, post-concussive amnesia}}
{{familytree | | | |!| | | | | | | | | |!| | | | }}
{{familytree | | | |!| | | | | | | | | |!| | | | }}
{{familytree | | |B01| | | | | | | | |!| | | | B01= Measure CBC, TSH, creatinine, electrolites,  
{{familytree | | |B01| | | | | | | | |!| | | | B01= Measure CBC, creatinine, electrolites, and
glucose, vitamin B12, and folic acid to reveal cause|B02= Concussion, post-concussive amnesia}}
glucose to reveal cause|B02= Concussion, post-concussive amnesia}}
{{familytree | | | | | | | | | | | | | |!| | | | }}
{{familytree | | | | | | | | | | | | | |!| | | | }}
{{familytree | | | | | | | | | | | | | |!| | | | }}
{{familytree | | | | | | | | | | | | | |!| | | | }}

Revision as of 10:27, 18 August 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Moises Romo, M.D.

Overview

Amnesia is a condition in which memory is disturbed or lost. The causes of amnesia can be organic or functional. Organic causes include damage to the brain through trauma or disease or the use of certain (generally sedative) drugs. Functional causes are psychological factors, such as defense mechanisms. Hysterical post-traumatic amnesia is an example of this. Amnesia may also be spontaneous, in the case of transient global amnesia. This global type of amnesia is more common in middle-aged to elderly people, particularly males, and usually lasts less than 24 hours. Memory loss can be partial or total and is normally expected as we get older.

Causes

Life Threatening Causes

  • Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.
  • Most acute causes of amnesia are considered life-threatening, among them, are the following:
    • Electrolyte imbalances
    • Head trauma
    • Hypoglycemia
    • Infections

Common Causes

  • Alzheimer
  • Vascular dementia
  • Frontotemporal dementia
  • Vitamin deficiency
  • Depression

Diagnosis

Shown below is an algorithm summarizing the diagnosis of amnesia according to the the American Academy of Neurology guidelines.

 
 
 
 
 
 
 
Patient with amnesia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Acute onset
 
 
 
 
 
 
 
Chronic onset
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Measure vitamin B12, and folic acid, and TSH
 
Abnormal?
 
Yes
 
Vitamin deficiency, hypothyroidism
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Fluctuating course, inattention, disorganized thinking, or altered level of consciousness?
 
 
 
 
 
 
 
Positive for SIGE CAPS questionary?
 
Yes
 
Depression
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Delirium
 
 
 
 
 
 
 
Dementia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Take history and perform physical examination
 
 
 
 
 
 
 
Take history and perform physical examination
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
History of head trauma?
 
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
Concussion, post-concussive amnesia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Measure CBC, creatinine, electrolites, and glucose to reveal cause
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Initial short term memory loss
 
Vascular risk factors, imaging evidence of cerebrovascular involvement
 
Young age, behavioral symptoms or language impairment
 
 
Bradikinesia or features of parkinsonism,

fluctuating cognition, visual

hallucinations
 
 
 
Dementia occuring 1 year after onset of Parkinson disease
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Alzheimer disease
 
Vascular dementia
 
Frontotemporal dementia
 
 
Dementia with Lewy bodies
 
 
 
Parkinson disease dementia
 
 

Do's

  • The content in this section is in bullet points.

Don'ts

  • The content in this section is in bullet points.

References

Template:WikiDoc Sources