Membranous glomerulonephritis laboratory findings: Difference between revisions

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==Overview==
==Overview==
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal among patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name].
==Laboratory Findings==
==Laboratory Findings==
 
* Comprehensive chemistry panel including serum albumin
*There are no diagnostic laboratory findings associated with [disease name].
* Complete blood count
OR
* Urinalysis with examination of the sediment
*An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
* 24-hour urine collection for protein quantification and creatinine clearance
*[Test] is usually normal among patients with [disease name].
* ANA and, if positive, anti-double-stranded DNA (anti-dsDNA), anti-Sm, anti-Ro/SSA, and anti-La/SSB antibodies
*Laboratory findings consistent with the diagnosis of [disease name] include:
* Tests for hepatitis B and C viruses and the human immunodeficiency virus (HIV) (see "Hepatitis B virus: Screening and diagnosis", section on 'Diagnostic algorithms' and "Diagnosis and evaluation of chronic hepatitis C virus infection", section on 'Testing algorithm' and "Screening and diagnostic testing for HIV infection", section on 'Testing algorithm')
**[Abnormal test 1]
* Serum C3 and C4 complement levels
**[Abnormal test 2]
* In patients older than 50 years – serum free light chains (SFLCs) and serum protein electrophoresis (SPEP) with immunofixation
**[Abnormal test 3]
* Chest radiograph (or computed tomography [CT] of the chest in patients with a history of smoking or asbestos exposure)
 
* Anti-PLA2R antibody (by enzyme-linked immunosorbent assay [ELISA])
*Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].


==References==
==References==

Revision as of 12:58, 20 May 2018

Membranous glomerulonephritis Microchapters

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Overview

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Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Laboratory Findings

  • Comprehensive chemistry panel including serum albumin
  • Complete blood count
  • Urinalysis with examination of the sediment
  • 24-hour urine collection for protein quantification and creatinine clearance
  • ANA and, if positive, anti-double-stranded DNA (anti-dsDNA), anti-Sm, anti-Ro/SSA, and anti-La/SSB antibodies
  • Tests for hepatitis B and C viruses and the human immunodeficiency virus (HIV) (see "Hepatitis B virus: Screening and diagnosis", section on 'Diagnostic algorithms' and "Diagnosis and evaluation of chronic hepatitis C virus infection", section on 'Testing algorithm' and "Screening and diagnostic testing for HIV infection", section on 'Testing algorithm')
  • Serum C3 and C4 complement levels
  • In patients older than 50 years – serum free light chains (SFLCs) and serum protein electrophoresis (SPEP) with immunofixation
  • Chest radiograph (or computed tomography [CT] of the chest in patients with a history of smoking or asbestos exposure)
  • Anti-PLA2R antibody (by enzyme-linked immunosorbent assay [ELISA])

References

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