Megestrol

Megestrol

Clinical data
Pregnancy category	contraindicated
ATC code	G03AC05 (WHO) G03DB02 (WHO), L02AB01 (WHO)
Pharmacokinetic data
Elimination half-life	34 hours
Identifiers
IUPAC name 17-acetyl-17-hydroxy-6,10, 13-trimethyl-2,8,9,11,12,14,15,16- octahydro-1H-cyclopenta[ a] phenanthren-3-one
CAS Number	3562-63-8
PubChem CID	19090
DrugBank	APRD01092
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H30O3
Molar mass	342.472 g/mol

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Megestrol is a progesterone derivative with antineoplastic properties used in the treatment of advanced carcinoma of the breast and endometrium. When given in relatively high doses, Megestrol can substantially increase appetite in most individuals, even those with advanced cancer.

Megestrol Acetate Oral Suspension (a form of Megestrol) is used primarily as an appetite enhancer. The method of appetite enhancement is not known, but it CAN cause hyperglycemia also known as high blood sugar[ http://www.megacees.com/megacees-side-effects.html].
Currently, it is manufactured under the trade name Megace [1]

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