Malaria natural history, complications, and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History

  • Severe malaria is almost exclusively caused by P. falciparum infection and usually arises 6-14 days after infection.[1]
  • Severe malaria can progress extremely rapidly and cause death within hours or days.[1] In the most severe cases of the disease fatality rates can exceed 20%, even with intensive care and treatment.[2]

Complications

References

  1. 1.0 1.1 Trampuz A, Jereb M, Muzlovic I, Prabhu R (2003). "Clinical review: Severe malaria". Crit Care. 7 (4): 315–23. PMID 12930555.
  2. Kain K, Harrington M, Tennyson S, Keystone J (1998). "Imported malaria: prospective analysis of problems in diagnosis and management". Clin Infect Dis. 27 (1): 142–9. PMID 9675468.


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