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{{CMG}}
{{CMG}}
==Overview==
==Overview==
'''Macrocytosis''' is the enlargement of [[red blood cell]]s with near-constant [[haemoglobin]] concentration, and is defined by a [[mean corpuscular volume]] (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).  
An ECG may be helpful in the diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic of megaloblastic anemia include  T wave inversions, ST-segment depression, LVH
 
==Electrocardiogram==
 
*An ECG may be helpful in the diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic ofmegaloblastic anemia include:<ref name="pmid25838876">{{cite journal |vauthors=Shamkani WA, Jafar NS, Narayanan SR, Rajappan AK |title=Acute Myocardial Infarction in a Young Lady due to Vitamin B12 Deficiency Induced Hyperhomocysteinemia |journal=Heart Views |volume=16 |issue=1 |pages=25–9 |date=2015 |pmid=25838876 |pmc=4379639 |doi=10.4103/1995-705X.152998 |url=}}</ref><ref name="pmid24959433">{{cite journal |vauthors=Gv S, Pk S, Herur A, Chinagudi S, Patil SS, Ankad RB, Badami SV |title=Correlation Between Haemoglobin Level and Electrocardiographic (ECG) Findings in Anaemia: A Cross-Sectional Study |journal=J Clin Diagn Res |volume=8 |issue=4 |pages=BC04–6 |date=April 2014 |pmid=24959433 |pmc=4064835 |doi=10.7860/JCDR/2014/8966.4202 |url=}}</ref>
** T wave inversions
** ST segment depression
**LVH
* As Vitamin B12 deficiency associaited hyperhomocysteinemia can cause acute myocardial infection, features of myocardial infection can appear in ECG.<ref name="pmid25838876">{{cite journal |vauthors=Shamkani WA, Jafar NS, Narayanan SR, Rajappan AK |title=Acute Myocardial Infarction in a Young Lady due to Vitamin B12 Deficiency Induced Hyperhomocysteinemia |journal=Heart Views |volume=16 |issue=1 |pages=25–9 |date=2015 |pmid=25838876 |pmc=4379639 |doi=10.4103/1995-705X.152998 |url=}}</ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

An ECG may be helpful in the diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic of megaloblastic anemia include T wave inversions, ST-segment depression, LVH

Electrocardiogram

  • An ECG may be helpful in the diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic ofmegaloblastic anemia include:[1][2]
    • T wave inversions
    • ST segment depression
    • LVH
  • As Vitamin B12 deficiency associaited hyperhomocysteinemia can cause acute myocardial infection, features of myocardial infection can appear in ECG.[1]

References

  1. 1.0 1.1 Shamkani WA, Jafar NS, Narayanan SR, Rajappan AK (2015). "Acute Myocardial Infarction in a Young Lady due to Vitamin B12 Deficiency Induced Hyperhomocysteinemia". Heart Views. 16 (1): 25–9. doi:10.4103/1995-705X.152998. PMC 4379639. PMID 25838876.
  2. Gv S, Pk S, Herur A, Chinagudi S, Patil SS, Ankad RB, Badami SV (April 2014). "Correlation Between Haemoglobin Level and Electrocardiographic (ECG) Findings in Anaemia: A Cross-Sectional Study". J Clin Diagn Res. 8 (4): BC04–6. doi:10.7860/JCDR/2014/8966.4202. PMC 4064835. PMID 24959433.

gl:Anemia megaloblástica he:אנמיה מגלובלסטית it:Anemia megaloblastica sl:Megaloblastna anemija sr:Мегалобластна анемија


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