MTMR3
| Myotubularin related protein 3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | MTMR3 ; FYVE-DSP1; KIAA0371; ZFYVE10 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 23662 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE MTMR3 202197 at tn.png | |||||||||||
| File:PBB GE MTMR3 202198 s at tn.png | |||||||||||
| File:PBB GE MTMR3 211507 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Myotubularin related protein 3, also known as MTMR3, is a human gene.[1]
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.[1]
References
 | This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it. |